NCT02738177 is a Phase 2 clinical trial of Misoprostol in Cervical Ripening, sponsored by Cairo University.

Who is sponsoring NCT02738177?

NCT02738177 is sponsored by Cairo University.

What drugs are being tested in NCT02738177?

Interventions in NCT02738177: Misoprostol, Isosorbide-5-mononitrate, misoprostol and Isosorbide-5-mononitrate.

What condition does NCT02738177 study?

NCT02738177 studies Cervical Ripening.

Is NCT02738177 still recruiting?

NCT02738177 is currently status unknown. Last updated 13 April 2016.

Last reviewed 2016-04-13 · How we verify

NCT02738177

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Misoprostol Versus Effox (Individually or in Combination) as Cervical Ripening Agent Prior to 1st Trimesteric Surgical Evacuation

Status unknown Phase 2 Last updated 13 April 2016

What this trial tests

Phase 2 trial testing Misoprostol in Cervical Ripening in 90 participants. Status unknown.

Timeline

1 November 2015

Primary endpoint
1 June 2016

Quick facts

Lead sponsor	Cairo University
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Masking	single
Primary purpose	treatment
Enrollment	90
Start date	1 November 2015
Primary completion	1 June 2016
Sites	1 location across Egypt

Drugs / interventions tested

Misoprostol (Misoprostol) — full drug profile →
Isosorbide-5-mononitrate — full drug profile →
misoprostol and Isosorbide-5-mononitrate — full drug profile →

Conditions studied

Cervical Ripening — all drugs for Cervical Ripening →

Sponsor

Cairo University

Who can join

Adults 18 to 40, female only, with Cervical Ripening. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

cervical dilatation
Time frame: 4 hours after receiving the drug
tested by the number of the largest Hegar's dilator passed without resistance

Sponsor's own description

Ninety healthy pregnant women candidate for surgical evacuation after confirming 1st trimester pregnancy loss were enrolled in the study. They were randomized in three groups; misoprostol group in which 30 candidates were receive 2 tablets of misoprostol (i.e. 400 ug) 4 hrs prior to surgical evacuation, Effox group in which 30 candidates were received 2 tablets of Effox (i.e 40 mg) 4 hrs prior to surgical evacuation \& combination therapy group in which 30 candidates were received 1 tablets of misoprostol 200ug \& 1 tablets of Effox 20 mg 4 hrs prior to surgical evacuation. For all participants, the route of administration was the intravaginal route 1ry outcomes included cervical consistency \& dilatation immediately before the procedure. 2ry outcomes included total duration of the operation and the occurrence of drug-related side effects

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Misoprostol

Trials testing the same drug.

NCT07353281 — Carbetocin vs Misoprostol for Postpartum Hemorrhage Prevention · NA · not yet recruiting
NCT06669533 — Use Misoprostol to Optimize Prevention of Cervical Cancer · NA · recruiting
NCT07416487 — Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor · NA · completed
NCT06765473 — Comparison Between Preoperative Vaginal and Postoperative Sublingual Misoprostol for Prevention of Postpartum Hemorrhage · Phase 3 · not yet recruiting
NCT06452719 — Letrozole and Misoprostol for Early Pregnancy Loss Management · Phase 2 · recruiting

Other recruiting trials for Cervical Ripening

Currently open trials in the same condition.

NCT06591247 — Membrane Stripping for Cervical Ripening · NA · recruiting
NCT07121634 — Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial · NA · active not recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02738177 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 13 April 2016

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02738177.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing