NCT02732925 (MELODY) is a NA clinical trial of Arm 2 Balloon Kyphoplasty in Multiple Myeloma, sponsored by Royal National Orthopaedic Hospital NHS Trust.

Who is sponsoring NCT02732925?

NCT02732925 is sponsored by Royal National Orthopaedic Hospital NHS Trust.

What drugs are being tested in NCT02732925?

Interventions in NCT02732925: Arm 2 Balloon Kyphoplasty, Conservative Management.

What condition does NCT02732925 study?

NCT02732925 studies Multiple Myeloma.

Is NCT02732925 still recruiting?

NCT02732925 is currently terminated. Last updated 6 April 2018.

Last reviewed 2018-04-06 · How we verify

NCT02732925: MELODY

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

To Compare Conservative Management Vs. Balloon Kyphoplasty in the Treatment of VCFs in Patients With Multiple Myeloma

Terminated NA Last updated 6 April 2018

What this trial tests

NA trial testing Arm 2 Balloon Kyphoplasty in Multiple Myeloma in 2 participants. Terminated before completion.

Timeline

9 June 2017

Primary endpoint
28 March 2018

28 March 2018

Quick facts

Lead sponsor	Royal National Orthopaedic Hospital NHS Trust
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	treatment
Enrollment	2
Start date	9 June 2017
Primary completion	28 March 2018
Estimated completion	28 March 2018
Sites	1 location across United Kingdom

Drugs / interventions tested

Arm 2 Balloon Kyphoplasty
Conservative Management

Conditions studied

Multiple Myeloma — all drugs for Multiple Myeloma →

Sponsor

Royal National Orthopaedic Hospital NHS Trust

Who can join

Adults 18 to 80, any sex, with Multiple Myeloma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to determine whether surgical treatment, balloon kyphoplasty is more effective compared to conservative treatment alone (sham procedure) when assessing clinical, translational, radiological \& patient outcomes in patients with multiple myeloma. Subjects will be recruited to the study if they have VAS score ≥ 6 and has given informed consent to participate in the Melody Study will be randomised to Arm 1 Sham Procedure and Conservative treatment or Arm 2 Balloon Kyphoplasty and Conservative treatment. Subjects recruited to Arm 1 (Sham Procedure and Conservative treatment) can cross over into Arm 2 (Balloon Kyphoplasty and Conservative Treatment) if they have a VAS score ≥ 6 between 8-12 weeks.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Multiple Myeloma

Currently open trials in the same condition.

NCT07200102 — Selinexor Maintenance Post CAR-T Cell Therapy for Multiple Myeloma · Phase 1 · recruiting
NCT07340853 — CRISPR Delivered Anti-BCMA Car-T Therapy for Relapsed or Refractory Multiple Myeloma · Phase 1 · recruiting
NCT07454382 — A Study of Elranatamab and Cyclophosphamide in People With Multiple Myeloma · Phase 2 · recruiting
NCT07266441 — A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma · Phase 2 · recruiting
NCT07258511 — A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With · Phase 3 · recruiting

Other Royal National Orthopaedic Hospital NHS Trust trials

Trials by the same sponsor.

NCT07438873 — Dynamic Lycra Garments for Hip Dysplasia Feasibility Study · NA · not yet recruiting
NCT07361913 — RA Anatomy - VRvST Study · NA · not yet recruiting
NCT05018039 — Feasibility and Acceptability of Collaborative Care for People With Musculoskeletal and Mental Problems · NA · unknown
NCT04385472 — Musculoskeletal Imaging of Runners · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02732925 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Royal National Orthopaedic Hospital NHS Trust
Last refreshed: 6 April 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02732925.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing