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NCT02720939

ASD-specific Induced Pluripotent Stem Cells for Disease Modeling

Completed Last updated 2 September 2021
What this trial tests

trial in Autism Spectrum Disorder in 20 participants. Completed in 31 December 2016.

Timeline
1 January 2016
Primary endpoint
31 December 2016
31 December 2016

Quick facts

Lead sponsorNational Taiwan University Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment20
Start date1 January 2016
Primary completion31 December 2016
Estimated completion31 December 2016
Sites1 location across Taiwan

Conditions studied

Sponsor

National Taiwan University Hospital

Who can join

Eligibility, any sex, with Autism Spectrum Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Specific Aims: 1. To generate induced-pluripotent stem cells (iPSCs) from peripheral blood mononuclear cells (PBMCs) isolated from whole blood of ASD probands and healthy controls. 2. To derive neural progenitor cells (NPCs) and neurons from iPSCs of ASD probands and healthy controls and compare differences between patients and healthy controls to investigate the cellular phenotype of ASD and uncover the pathophysiology of the disease.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Ethical and Safety Issues of Stem Cell-Based Therapy.
    Volarevic V, Markovic BS, Gazdic M, Volarevic A, et al · · 2018 · cited 552× · PMID 29333086 · DOI 10.7150/ijms.21666
  2. Induced Pluripotent (iPSC) and Mesenchymal (MSC) Stem Cells for In Vitro Disease Modeling and Regenerative Medicine.
    Panferov E, Dodina M, Reshetnikov V, Ryapolova A, et al · · 2025 · cited 8× · PMID 40565081 · DOI 10.3390/ijms26125617
  3. Cell reprogramming: methods, mechanisms and applications.
    Zhu F, Nie G. · · 2025 · cited 4× · PMID 40140235 · DOI 10.1186/s13619-025-00229-x

Verify or expand the search:

Other recruiting trials for Autism Spectrum Disorder

Currently open trials in the same condition.

Other National Taiwan University Hospital trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02720939.

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