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NCT02720939
ASD-specific Induced Pluripotent Stem Cells for Disease Modeling
trial in Autism Spectrum Disorder in 20 participants. Completed in 31 December 2016.
31 December 2016
Quick facts
| Lead sponsor | National Taiwan University Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 1 January 2016 |
| Primary completion | 31 December 2016 |
| Estimated completion | 31 December 2016 |
| Sites | 1 location across Taiwan |
Conditions studied
- Autism Spectrum Disorder — all drugs for Autism Spectrum Disorder →
Sponsor
National Taiwan University Hospital
Who can join
Eligibility, any sex, with Autism Spectrum Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Specific Aims: 1. To generate induced-pluripotent stem cells (iPSCs) from peripheral blood mononuclear cells (PBMCs) isolated from whole blood of ASD probands and healthy controls. 2. To derive neural progenitor cells (NPCs) and neurons from iPSCs of ASD probands and healthy controls and compare differences between patients and healthy controls to investigate the cellular phenotype of ASD and uncover the pathophysiology of the disease.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Ethical and Safety Issues of Stem Cell-Based Therapy.
Volarevic V, Markovic BS, Gazdic M, Volarevic A, et al · · 2018 · cited 552× · PMID 29333086 · DOI 10.7150/ijms.21666 -
Induced Pluripotent (iPSC) and Mesenchymal (MSC) Stem Cells for In Vitro Disease Modeling and Regenerative Medicine.
Panferov E, Dodina M, Reshetnikov V, Ryapolova A, et al · · 2025 · cited 8× · PMID 40565081 · DOI 10.3390/ijms26125617 -
Cell reprogramming: methods, mechanisms and applications.
Zhu F, Nie G. · · 2025 · cited 4× · PMID 40140235 · DOI 10.1186/s13619-025-00229-x
Verify or expand the search:
- PubMed search for NCT02720939
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other National Taiwan University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02720939 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
- Last refreshed: 2 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02720939.
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