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NCT02718729
Anastomotic Leakage Following Laparoscopic Resection for Rectal Cancer
NA trial testing Laparoscopic resection for rectal cancer in Anastomotic Leakage in 59 participants. Completed in 1 June 2017.
1 January 2017
Quick facts
| Lead sponsor | Mansoura University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 59 |
| Start date | 1 June 2015 |
| Primary completion | 1 January 2017 |
| Estimated completion | 1 June 2017 |
| Sites | 2 locations across Italy, Egypt |
Drugs / interventions tested
- Laparoscopic resection for rectal cancer
Conditions studied
- Anastomotic Leakage — all drugs for Anastomotic Leakage →
Sponsor
Mansoura University
Who can join
Eligibility, any sex, with Anastomotic Leakage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Anastomotic leak (AL) is a breakdown of a suture line in a surgical anastomosis with a subsequent leakage of the luminal content. Anastomotic leakage occurs commonly in rectal and esophageal anastomosis than the other parts of the alimentary tract due to technical difficulties in accessing these areas and their easily compromised blood supply. Anastomotic leakage is the most feared complication following rectal resection and anastomosis. The incidence of anastomotic leakage ranges from 2.8% to more than 15%, with mortality rate more than 30%. Subclinical anastomotic failure may occur in up to 51% of patients. Anastomotic leakage leads to increase the rate of secondary interventions, re-operations, longer postoperative hospital stay, increased cost, and major impact on the patient's quality of life. In the medium to long term, patient may be unfit for post-operative adjuvant therapy with decreased the disease survival. Furthermore anastomotic leakage itself may increase the local recurrence, a reduction in overall survival, and a large proportion of patients are left with a permanent stoma.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT02718729
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Anastomotic Leakage
Currently open trials in the same condition.
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- NCT07208786 — Pre-emptive Endoscopic Vacuum Therapy Reduces the Incidence of Anastomotic Leakage After Colorectal Cancer Surgery · NA · recruiting
- NCT06865638 — Efficacy and Safety of Colorectal Anastomotic Leak Testing · NA · recruiting
- NCT06464978 — Stapler Reinforcement Patches Compared to Standard Staplers in Gastrojejunostomy · NA · recruiting
- NCT05826743 — Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy · NA · recruiting
Other Mansoura University trials
Trials by the same sponsor.
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- NCT07509567 — Conventional Palatal Crib Versus Bonded Spurs for Anterior Open Bite Treatment · NA · not yet recruiting
- NCT07393178 — Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones · NA · not yet recruiting
- NCT07436182 — Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. · Phase 4 · not yet recruiting
- NCT07534943 — Effectiveness of Oleanolic Acid as Intracanal Medicament on Infectious/Inflammatory Contents in Teeth With Apical Period · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02718729 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mansoura University
- Last refreshed: 29 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02718729.
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