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Predictive Biomarkers for IGF1R Targeted Therapy in Ovarian Cancer
The main goal of this study is to employ a novel proteomic approach to identify predictive tumor biomarkers that will increase the efficacy of insulin-like growth factor (IGF1R) targeted therapy in epithelial ovarian cancer. It is expected that these predictive biomarkers will be applied to increase the response rate in selected groups of patients.
Details
| Lead sponsor | Hillel Yaffe Medical Center |
|---|---|
| Status | UNKNOWN |
| Enrolment | 20 |
| Start date | 2016-05 |
| Completion | 2019-05 |
Conditions
- Ovarian Cancer
Interventions
- IGF1R antibody MK0646
- Saline solution
Primary outcomes
- Responsive to IGF1R therapy — One year
Mean tumor volume will be calculated and growth inhibition will be reported as the percentage decrease of tumor volume compared with the control.
Countries
Israel