NCT02708927: EMOSOCIAL-MS

Emotional Processing, Family Life, Friendship and Social Integration in Patients With Multiple Sclerosis

Completed NA Last updated 5 February 2019

What this trial tests

NA trial testing Clinical evaluation in Multiple Sclerosis in 91 participants. Completed in 28 January 2019.

Timeline

3 March 2016

Primary endpoint
28 January 2019

28 January 2019

Quick facts

Lead sponsor	University Hospital, Bordeaux
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	diagnostic
Enrollment	91
Start date	3 March 2016
Primary completion	28 January 2019
Estimated completion	28 January 2019
Sites	2 locations across France

Drugs / interventions tested

• Clinical evaluation — full drug profile →
• Cognitive evaluation

Conditions studied

• Multiple Sclerosis — all drugs for Multiple Sclerosis →

Sponsor

University Hospital, Bordeaux

Who can join

Adults 18 to 45, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In addition to the physical, cognitive and psychological symptoms experienced by individuals with Multiple Sclerosis (MS), there is new research which indicates that some individuals with MS have a deficit in emotional processing, specifically, facial affect recognition. Emotional processing is defined as "a central aspect of social cognition". Models of social cognition indicate that emotional processing is an essential component of interpersonal relationships. The failure to accurately perceive other's emotions has been shown to lead to difficulty in social relationships, misinterpreting other's affect, and consequently, inappropriate responding.

However, even though a significant number of individuals with MS have impairments in emotional processing, we do not yet have an understanding of how these impairments affect the social functioning of individuals with MS, including the impact of these deficits on family structure. It is well-known that MS impacts one's social functioning including factors such as employment, daily living activities and interpersonal relationships. Recently a strong correlation was observed between reduced social participation in MS and quality of life. There is evidence to suggest that emotional processing deficits lie at the heart of this reduced social participation in persons with MS, leading to decreased social functioning and thus reduced quality of life. However, to date, this hypothesis has not been tested.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.