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NCT02706431
Oxygenation by 100% Oxygen Via High Flow Nasal Cannula in Surgical Patients
NA trial testing Hyperventilation in Anaesthesia, General in 31 participants. Completed in 1 September 2016.
30 June 2016
Quick facts
| Lead sponsor | Karolinska University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 31 |
| Start date | 1 December 2015 |
| Primary completion | 30 June 2016 |
| Estimated completion | 1 September 2016 |
Drugs / interventions tested
- Hyperventilation
Conditions studied
- Anaesthesia, General — all drugs for Anaesthesia, General →
- Anesthesia, Intravenous — all drugs for Anesthesia, Intravenous →
- Ventilation — all drugs for Ventilation →
Sponsor
Karolinska University Hospital
Who can join
18 and older, any sex, with Anaesthesia, General or Anesthesia, Intravenous. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Oxygenation with high-flow nasal cannula with 100% oxygen has only been evaluated in a limited number of studies. Although data are convincing it is of importance to evaluate this new concept in our department before implementing it into clinical practice. The general purpose of this project is to evaluate a new ventilation strategy during ENT-surgery based on oxygenation with high-flow nasal cannula with 100% oxygen with focus on gas exchange.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Apnoeic oxygenation in adults under general anaesthesia using Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) - a physiological study.
Gustafsson IM, Lodenius Å, Tunelli J, Ullman J, et al · · 2017 · cited 160× · PMID 28403407 · DOI 10.1093/bja/aex036
Verify or expand the search:
- PubMed search for NCT02706431
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Hyperventilation
Trials testing the same drug.
- NCT04106869 — The Influence of Ventilation on Perioperative Neurocognitive Disorders · NA · withdrawn
- NCT03317652 — Effect of Sodium Nitroprusside on Cerebral Blood Flow · NA · completed
Other Karolinska University Hospital trials
Trials by the same sponsor.
- NCT07424690 — Catheter Ablation vs Conservative Care in Elderly Patients With Atrial Fibrillation · NA · not yet recruiting
- NCT06639191 — [177Lu]Lu-AKIR001 First-in-human Study · EARLY_PHASE1 · recruiting
- NCT03629977 — Timing of Renal Replacement Therapy in the Critically Ill Patients · recruiting
- NCT06983197 — Iatrogenic Deficiencies in ICU Patients With Prolonged Continuous Renal Replacement Therapy · not yet recruiting
- NCT06835816 — Amino Acid Supplementation in Continuous Renal Replacement Therapy · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02706431 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karolinska University Hospital
- Last refreshed: 19 December 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02706431.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing