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NCT02701504: SABOT

Undiagnosed Sleep Apnea and Bypass OperaTion

Completed Last updated 26 March 2020
What this trial tests

trial in Sleep Apnea in 1,000 participants. Completed in 31 March 2019.

Timeline
1 October 2013
Primary endpoint
31 March 2019
31 March 2019

Quick facts

Lead sponsorNational University of Singapore
StatusCompleted
Study typeOBSERVATIONAL
Enrollment1,000
Start date1 October 2013
Primary completion31 March 2019
Estimated completion31 March 2019
Sites1 location across Singapore

Conditions studied

Sponsor

National University of Singapore

Who can join

Adults 18 to 90, any sex, with Sleep Apnea. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Sleep apnea is a prevalent disorder in patients with coronary artery disease. Previous studies suggested sleep apnea was associated with coronary plaque burden and future adverse cardiovascular events after percutaneous coronary intervention. In the SABOT study, the investigators used a FDA-approved portable sleep device to diagnose sleep apnea, and evaluate the relationship between sleep apnea and cardiovascular outcomes after non-urgent coronary artery bypass surgery.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Sleep apnoea and cardiovascular outcomes after coronary artery bypass grafting.
    Koo CY, Aung AT, Chen Z, Kristanto W, et al · · 2020 · cited 17× · PMID 32423904 · DOI 10.1136/heartjnl-2019-316118
  2. Sleep apnea and recurrent heart failure hospitalizations after coronary artery bypass grafting.
    Teo YH, Tam WW, Koo CY, Aung AT, et al · · 2021 · cited 6× · PMID 34216202 · DOI 10.5664/jcsm.9442
  3. Sleep apnea and diabetes mellitus are independently associated with cardiovascular events and hospitalization for heart failure after coronary artery bypass grafting.
    Aung AT, Koo CY, Tam WW, Chen Z, et al · · 2020 · cited 6× · PMID 33303900 · DOI 10.1038/s41598-020-78700-9
  4. Obstructive sleep apnea and temporal changes in cardiac repolarization in patients undergoing coronary artery bypass grafting.
    Teo YH, Yong CL, Ou YH, Tam WW, et al · · 2024 · cited 2× · PMID 38163943 · DOI 10.5664/jcsm.10786
  5. Sleep Apnea and Cardiovascular Outcomes in Patients Undergoing Coronary Artery Bypass Grafting: 6-Year Follow-Up.
    Teo YH, Teo YN, Yong CL, Chan J, et al · · 2024 · PMID 39619393 · DOI 10.1016/j.jacasi.2024.08.012
  6. Concomitant Sleep Apnea and Diabetes Mellitus Are Independently Associated with Cardiovascular Events and Hospitalization for Heart Failure after Coronary Artery Bypass Grafting
    Aung A, Koo C, Tam WW, Chen Z, et al · · 2020 · DOI 10.21203/rs.3.rs-30720/v1

Verify or expand the search:

Other recruiting trials for Sleep Apnea

Currently open trials in the same condition.

Other National University of Singapore trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02701504.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing