Who is sponsoring NCT02696824?

NCT02696824 is sponsored by University of Miami.

What drugs are being tested in NCT02696824?

Interventions in NCT02696824: Cognitive Behavioral Therapy for Adherence and Depression.

What condition does NCT02696824 study?

NCT02696824 studies Immunodeficiency Virus, Human, Depressive Symptoms.

Is NCT02696824 still recruiting?

NCT02696824 is currently completed. Last updated 19 January 2021.

Last reviewed 2021-01-19 · How we verify

NCT02696824

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effectiveness of Nurse-delivered Care for Adherence/Mood in HIV in South Africa

Completed NA Last updated 19 January 2021

What this trial tests

NA trial testing Cognitive Behavioral Therapy for Adherence and Depression in Immunodeficiency Virus, Human in 161 participants. Completed in 9 June 2020.

Timeline

19 July 2016

Primary endpoint
17 October 2019

9 June 2020

Quick facts

Lead sponsor	University of Miami
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	161
Start date	19 July 2016
Primary completion	17 October 2019
Estimated completion	9 June 2020
Sites	3 locations across South Africa, United States

Drugs / interventions tested

Cognitive Behavioral Therapy for Adherence and Depression

Conditions studied

Immunodeficiency Virus, Human — all drugs for Immunodeficiency Virus, Human →
Depressive Symptoms — all drugs for Depressive Symptoms →

Sponsor

University of Miami

Who can join

18 and older, any sex, with Immunodeficiency Virus, Human or Depressive Symptoms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to conduct a two-arm effectiveness trial in Cape Town, South Africa of a Xhosa-adapted, nurse-delivered, cognitive behavioral therapy (CBT) treatment for depression and adherence, integrated into the HIV care setting in patients with HIV who did not achieve viral suppression from first-line treatment. The CBT treatment will be compared to enhanced usual care (Enhanced Treatment As Usual - ETAU) on study endpoints (as described in study endpoints section below).

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Primary-level worker interventions for the care of people living with mental disorders and distress in low- and middle-income countries.
van Ginneken N, Chin WY, Lim YC, Ussif A, et al · · 2021 · cited 89× · PMID 34352116 · DOI 10.1002/14651858.cd009149.pub3
Treating depression and improving adherence in HIV care with task-shared cognitive behavioural therapy in Khayelitsha, South Africa: a randomized controlled trial.
Safren SA, O'Cleirigh C, Andersen LS, Magidson JF, et al · · 2021 · cited 63× · PMID 34708929 · DOI 10.1002/jia2.25823
Nurse-Delivered Cognitive Behavioral Therapy for Adherence and Depression Among People Living With HIV (the Ziphamandla Study): Protocol for a Randomized Controlled Trial.
Joska JA, Andersen LS, Smith-Alvarez R, Magidson J, et al · · 2020 · cited 16× · PMID 32012114 · DOI 10.2196/14200

Verify or expand the search:

Other University of Miami trials

Trials by the same sponsor.

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NCT06077071 — MRIdian "RADAR" Trial · NA · not yet recruiting
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NCT07322289 — Antibiotic-coated Braided Suture Study · NA · not yet recruiting
NCT07469592 — eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02696824 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Miami
Last refreshed: 19 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02696824.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing