NCT02691546: SCOPE

Screening for Chronic Kidney Disease (CKD) Among Older People Across Europe (SCOPE)

Completed Last updated 24 June 2020

What this trial tests

trial testing blood sample collection in Chronic Kidney Diseases in 2,434 participants. Completed in 10 March 2020.

Timeline

8 August 2016

Primary endpoint
10 March 2020

10 March 2020

Quick facts

Lead sponsor	Istituto Nazionale di Ricovero e Cura per Anziani
Status	Completed
Study type	OBSERVATIONAL
Enrollment	2,434
Start date	8 August 2016
Primary completion	10 March 2020
Estimated completion	10 March 2020
Sites	9 locations across Italy, Netherlands, Austria, Israel, Germany, Poland, Spain

Drugs / interventions tested

• blood sample collection — full drug profile →

Conditions studied

• Chronic Kidney Diseases — all drugs for Chronic Kidney Diseases →

Sponsor

Istituto Nazionale di Ricovero e Cura per Anziani — full company profile →

Who can join

75 and older, any sex, with Chronic Kidney Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The SCOPE study is an observational, multicenter, prospective cohort study aimed at evaluating a 2-year screening programme for CKD in a population of older patients, aged 75 years or more, in seven European Countries, in an attempt to investigate whether and to which extent currently available screening methods may identify older people at risk of worsening kidney function.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

1. Design and methodology of the screening for CKD among older patients across Europe (SCOPE) study: a multicenter cohort observational study.
   Corsonello A, Tap L, Roller-Wirnsberger R, Wirnsberger G, et al · · 2018 · cited 25× · PMID 30309342 · DOI 10.1186/s12882-018-1030-2
2. Impaired kidney function is associated with lower quality of life among community-dwelling older adults : The screening for CKD among older people across Europe (SCOPE) study.
   Artzi-Medvedik R, Kob R, Fabbietti P, Lattanzio F, et al · · 2020 · cited 20× · PMID 33008306 · DOI 10.1186/s12877-020-01697-3
3. Chronic kidney disease in the context of multimorbidity patterns: the role of physical performance : The screening for CKD among older people across Europe (SCOPE) study.
   Corsonello A, Fabbietti P, Formiga F, Moreno-Gonzalez R, et al · · 2020 · cited 20× · PMID 33008303 · DOI 10.1186/s12877-020-01696-4
4. Association between kidney function, nutritional status and anthropometric measures in older people : The Screening for CKD among Older People across Europe (SCOPE) study.
   Guligowska A, Corsonello A, Pigłowska M, Roller-Wirnsberger R, et al · · 2020 · cited 18× · PMID 33008315 · DOI 10.1186/s12877-020-01699-1
5. Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts.
   Zhang K, Yang R, Chen J, Qi E, et al · · 2020 · cited 11× · PMID 32478052 · DOI 10.3389/fbioe.2020.00428
6. Transient versus stable nature of fear of falling over 24 months in community-older persons with falls- data of the EU SCOPE project on Kidney function.
   Freiberger E, Fabbietti P, Corsonello A, Lattanzio F, et al · · 2022 · cited 8× · PMID 35999522 · DOI 10.1186/s12877-022-03357-0
7. The Possible Impact of Aortic Stiffness on Quality of Late Life: An Exploratory Study.
   Tap L, Dommershuijsen LJ, Corsonello A, Lattanzio F, et al · · 2020 · cited 8× · PMID 32099342 · DOI 10.2147/cia.s239186
8. Is kidney function associated with cognition and mood in late life? : The Screening for CKD among Older People across Europe (SCOPE) study.
   Tap L, Corsonello A, Formiga F, Moreno-Gonzalez R, et al · · 2020 · cited 7× · PMID 33008359 · DOI 10.1186/s12877-020-01707-4