NCT02691195

Ultrasound-guided Serratus Plane Block for the Quality of Recovery After Modified Radical Mastectomy

Completed Phase 4 Last updated 6 March 2018

What this trial tests

Phase 4 trial testing Ropivacaine in Anesthesia in 72 participants. Completed in 14 June 2017.

Timeline

15 March 2016

Primary endpoint
12 June 2017

14 June 2017

Quick facts

Lead sponsor	Fujian Provincial Hospital
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	72
Start date	15 March 2016
Primary completion	12 June 2017
Estimated completion	14 June 2017
Sites	1 location across China

Drugs / interventions tested

• Ropivacaine (ROPIVACAINE) — full drug profile →
• 0.9% Nacl

Conditions studied

• Anesthesia — all drugs for Anesthesia →

Sponsor

Fujian Provincial Hospital

Who can join

Adults 18 to 60, female only, with Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Regional anesthesia improves quality of recovery after surgery in many studies. Ultrasound-guided serratus plane block is a novel technique which may be a viable alternative to current regional anesthetic techniques. This randomized, controlled trial is to examine the effects of ultrasound-guided serratus plane block anesthetic on the QoR after breast tumor resection.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Ultrasound-guided serratus plane block enhances pain relief and quality of recovery after breast cancer surgery: A randomised controlled trial.
   Yao Y, Li J, Hu H, Xu T, et al · · 2019 · cited 48× · PMID 31021882 · DOI 10.1097/eja.0000000000001004
2. Local Anesthetic Ropivacaine Exhibits Therapeutic Effects in Cancers.
   Xu P, Zhang S, Tan L, Wang L, et al · · 2022 · cited 13× · PMID 35186766 · DOI 10.3389/fonc.2022.836882