Last reviewed · How we verify
Optical Biopsy for Thoracic Lymph Nodes.
EUS-FNA is the recommended diagnostic examination of choice when patients present with suspected lower mediastinal lymph nodes on imaging. EUS-FNA is minimal invasive and low in costs, and although it has a good record in detecting diseases (eg confirm a nodal metastasis or granulomas) it has limitations in excluding diseases (missing metastases/ or granulomas) resulting in a false negative rate of 15-20%. Substantial limitations that most likely can be attributed to areas within the node that are not sampled during EUS-FNA tissue acquisition. Improved needle based EBUS/ EUS guided nodal diagnostics might result in improved quality of the fine needle aspirations, reduce in surgical diagnostic procedures , reduced costs and result in a shorter timebefore-treatment interval.
Details
| Lead sponsor | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) |
|---|---|
| Status | COMPLETED |
| Enrolment | 40 |
| Start date | Wed Jan 13 2016 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Wed Mar 22 2017 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Mediastinal Lymphadenopathy
- Non-small Cell Lung Carcinoma
- Sarcoidosis
Interventions
- Needle based confocal laser endomicroscopy (nCLE)
Countries
Netherlands