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NCT02683200
MRI-Guided Stereotactic Body Radiation Therapy in Treating Patients With Liver Metastases or Liver Cancer
EARLY_PHASE1 trial testing Image-Guided Adaptive Radiation Therapy in Adult Hepatocellular Carcinoma in 21 participants. Completed in 1 January 2022.
1 January 2022
Quick facts
| Lead sponsor | Jonsson Comprehensive Cancer Center |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 21 |
| Start date | 3 June 2015 |
| Primary completion | 1 January 2022 |
| Estimated completion | 1 January 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Image-Guided Adaptive Radiation Therapy
- Stereotactic Body Radiation Therapy — full drug profile →
Conditions studied
- Adult Hepatocellular Carcinoma — all drugs for Adult Hepatocellular Carcinoma →
- Metastatic Malignant Neoplasm in the Liver — all drugs for Metastatic Malignant Neoplasm in the Liver →
Sponsor
Jonsson Comprehensive Cancer Center — full company profile →
Who can join
18 and older, any sex, with Adult Hepatocellular Carcinoma or Metastatic Malignant Neoplasm in the Liver. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This pilot clinical trial studies magnetic resonance imaging (MRI)-guided stereotactic body radiation therapy (SBRT) in treating patients with liver metastases or liver cancer. SBRT is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may kill more tumor cells and cause less damage to normal tissue. Combining MRI with SBRT may help doctors to highlight the tissues surrounding the tumor better.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
MRIgRT head and neck anthropomorphic QA phantom: Design, development, reproducibility, and feasibility study.
Steinmann A, Alvarez P, Lee H, Court L, et al · · 2020 · cited 11× · PMID 31808949 · DOI 10.1002/mp.13951
Verify or expand the search:
- PubMed search for NCT02683200
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Image-Guided Adaptive Radiation Therapy
Trials testing the same drug.
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- NCT01507428 — Study of Positron Emission Tomography and Computed Tomography in Guiding Radiation Therapy in Patients With Stage III No · Phase 2 · unknown
Other recruiting trials for Adult Hepatocellular Carcinoma
Currently open trials in the same condition.
- NCT02379377 — 18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant · Phase 1 · recruiting
Other Jonsson Comprehensive Cancer Center trials
Trials by the same sponsor.
- NCT07229339 — Zipalertinib With Carboplatin and Pemetrexed for the Treatment of Resectable, Stage II-IIIB, Non-Small Cell Lung Cancer · Phase 2 · not yet recruiting
- NCT06448286 — PH Weighted Chemical Exchange Saturation Transfer MRI-Based Surgical Resection to Improve Survival in Patients With Glio · Phase 3 · not yet recruiting
- NCT07517211 — A Prospective Study of Physical Function in Adults Who Receive Systemic Therapy for Stage I-III Gastroesophageal Cancer, · not yet recruiting
- NCT07191717 — Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Resi · Phase 2 · not yet recruiting
- NCT07468903 — Focal Radiation Therapy (HDR-Brachytherapy) for the Treatment of Prostate Cancer · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02683200 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jonsson Comprehensive Cancer Center
- Last refreshed: 21 February 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02683200.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing