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Evaluation of the Effect of Appropriate Sedation for Patients After Gastrectomy: A Prospective Randomised Controlled Study
To evaluate the efficacy and safety of appropriate postoperative sedation with dexmedetomidine for patients after gastrectomy. Prospective randomised controlled study was conducted from October 2015 and December 2015 among patients after gastrectomy. The investigators are going to enroll patients who received abdominal surgeries. One group receive sedative along with analgesic and the other group analgesic only for the other group on the first 24 hours after surgeries and follow up for 3 days.
Details
| Lead sponsor | Chinese Medical Association |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 80 |
| Start date | 2016-01 |
Conditions
- Postoperative Sedation,Gastrectomy, Enhanced Recovery After Surgery
Interventions
- dexmedetomidine, tramadol and flurbiprofen
- tramadol and flurbiprofen
Primary outcomes
- postoperative pain assessed by Prince Henry Pain Scale — 1-3d after gastrectomy
assessed by Prince Henry Pain Scale by investigators at 8:00 am after surgeries until discharge from ICU - recovery of gastrointestinal function assessed by time to first defecation after surgery — 30 days after gastrectomy
assessed by time to first defecation after surgery - white blood cell count (10^9/L) — 1-3d after gastrectomy
evaluate postoperative inflammatory response, blood sample collected at 6:00am for 1-3d after gastrectomy - C-reactive protein (mg/L) — 1-3d after gastrectomy
evaluate postoperative inflammatory response, blood sample collected at 6:00am for 1-3d after gastrectomy
Countries
China