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Evaluation of the Effect of Appropriate Sedation for Patients After Abdominal Surgeries : A Prospective Randomised Controlled Study
To evaluate the efficacy and safety of appropriate postoperative sedation with dexmedetomidine for patients after abdominal surgeries.Prospective randomised controlled study was conducted among patients after abdominal surgeries began in October 2015.The investigators enroll patients who received abdominal surgeries. One group receive sedative along with analgesic and the other group analgesic only for the other group on the first 24 hours after surgeries and will follow up for 3 days.
Details
| Lead sponsor | Chinese Medical Association |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 154 |
| Start date | 2015-10 |
| Completion | 2016-01 |
Conditions
- Postoperative Sedation, Abdominal Surgery
Interventions
- Dexmedetomidine, tramadol and flurbiprofen
- tramadol and flurbiprofen
Primary outcomes
- postoperative pain — 1-3d after abdominal surgeries
assessed by Prince Henry Pain Scale by investigators at 8:00 am after surgeries until discharge from ICU - recovery of gastrointestinal function — from admission to 30 days after abdominal surgeries
assessed by time to first defecation - white blood cell count(10^9 /L) — 1-3d after abdominal surgeries
evaluation of postoperative inflammatory response, blood sample collected at 6:00am for 1-3d after surgeries - C-reactive protein(mg/L) — 1-3d after abdominal surgeries
evaluation of postoperative inflammatory response, blood sample collected at 6:00am for 1-3d after surgeries
Countries
China