Who is sponsoring NCT02657135?

NCT02657135 is sponsored by University of Pittsburgh.

What drugs are being tested in NCT02657135?

Interventions in NCT02657135: Cognitive/Neuropsychological Testing, Vestibular/Ocular-Motor Testing, Cervical (Neck) Evaluation, Sleep Evaluation, HDFT MRI, MR Spectroscopy (MRS), MEG (Magnetoencephalography).

What condition does NCT02657135 study?

NCT02657135 studies Traumatic Brain Injury (TBI).

Is NCT02657135 still recruiting?

NCT02657135 is currently completed. Last updated 23 July 2018.

Last reviewed 2018-07-23 · How we verify

NCT02657135: TEAM-TBI

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Targeted Evaluation, Action, & Monitoring of Traumatic Brain Injury

Completed NA Last updated 23 July 2018

What this trial tests

NA trial testing Cognitive/Neuropsychological Testing in Traumatic Brain Injury (TBI) in 95 participants. Completed in 23 March 2018.

Timeline

24 March 2014

Primary endpoint
23 March 2018

23 March 2018

Quick facts

Lead sponsor	University of Pittsburgh
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	health services research
Enrollment	95
Start date	24 March 2014
Primary completion	23 March 2018
Estimated completion	23 March 2018
Sites	1 location across United States

Drugs / interventions tested

Cognitive/Neuropsychological Testing
Vestibular/Ocular-Motor Testing
Cervical (Neck) Evaluation
Sleep Evaluation
HDFT MRI
MR Spectroscopy (MRS)
MEG (Magnetoencephalography)

Conditions studied

Traumatic Brain Injury (TBI) — all drugs for Traumatic Brain Injury (TBI) →

Sponsor

University of Pittsburgh

Who can join

Adults 18 to 60, any sex, with Traumatic Brain Injury (TBI). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

TEAM-TBI (Targeted Evaluation, Action, and Monitoring of Traumatic Brain Injury) is a research study that brings together TBI patients, advanced evaluation methods, and experts in a multi-faceted study to address the heterogeneity of TBI and to evaluate the effects self-help strategies might have on TBI outcomes.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

Evaluating Targeted Therapeutic Response With Predictive Blood-Based Biomarkers in Patients With Chronic Mild Traumatic Brain Injury.
Eagle SR, Puccio AM, Agoston DV, Soose R, et al · · 2023 · cited 6× · PMID 37360545 · DOI 10.1089/neur.2023.0003
MEG-Derived Symptom-Sensitive Biomarkers with Long-Term Test-Retest Reliability.
Krieger D, Shepard P, Soose R, Puccio A, et al · · 2021 · cited 6× · PMID 35054252 · DOI 10.3390/diagnostics12010084
Association of Plasma Biomarkers with Sleep Outcomes and Treatment Response After Mild Traumatic Brain Injury.
Eagle SR, Puccio AM, Agoston DV, Mancinelli M, et al · · 2023 · cited 4× · PMID 37095856 · DOI 10.1089/neur.2023.0002
Symptom-Dependent Changes in MEG-Derived Neuroelectric Brain Activity in Traumatic Brain Injury Patients with Chronic Symptoms.
Krieger D, Shepard P, Soose R, Puccio AM, et al · · 2021 · cited 4× · PMID 33806153 · DOI 10.3390/medsci9020020
Predictive Blood Biomarkers of Targeted Intervention for Chronic Mental Health Symptoms following Traumatic Brain Injury.
Eagle SR, Svirsky SE, Puccio AM, Borrasso A, et al · · 2025 · cited 2× · PMID 39323312 · DOI 10.1089/neu.2024.0245

Verify or expand the search:

Other recruiting trials for Traumatic Brain Injury (TBI)

Currently open trials in the same condition.

NCT07493096 — Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disor · recruiting
NCT06725108 — Hemodynamic ABI Monitor · recruiting

Other University of Pittsburgh trials

Trials by the same sponsor.

NCT05601206 — Collaborative Care Intervention for Cancer Patients and Their Family Caregivers -LITE · NA · not yet recruiting
NCT06652815 — Cognition, Metacognition, and Stigma in Patients With Suicidal Ideation · not yet recruiting
NCT06474286 — Prucalopride for Cognitive Functioning in Schizophrenia · NA · not yet recruiting
NCT06488469 — Behavioural Problems and Cognition in Children With Hypoglycemia Unawareness in Type-1 Diabetes Mellitus · NA · not yet recruiting
NCT06652802 — Effectiveness of Nurse-Conducted Brief Intervention (NCBI) Supplemented With Mobile for Preventing Alcohol Use Disorders · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02657135 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Pittsburgh
Last refreshed: 23 July 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02657135.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing