The Effect of Preoperative Topical Ketorolac 0.45% on Aqueous Cytokine Levels and Macular Thickness in Diabetic and Non Diabetic Patients Undergoing Cataract Surgery

NCT02646072 Phase 4 COMPLETED

The purpose of this study is to determine whether there is a relationship between inflammatory cytokines in the aqueous of the eye and thickness of the macula after treatment of topical ketorolac for patients undergoing cataract surgery.

Details

Lead sponsor	University of Malaya
Phase	Phase 4
Status	COMPLETED
Enrolment	80
Start date	2014-08
Completion	2015-06

Conditions

• Cystoid Macular Edema, Postoperative
• Diabetes Mellitus

Interventions

• Ketorolac tromethamine ophthalmic solution 0.45%

Primary outcomes

• Level of aqueous inflammatory cytokines post treatment as assessed using Bio-plex Pro Assays — 9 months
  Aqueous samples were analyzed at the same after complete samples collection.

Countries

Malaysia