NCT02643940 (IMPACT-CTO) is a clinical trial in Acute Coronary Syndrome, sponsored by Mid and South Essex NHS Foundation Trust.

Who is sponsoring NCT02643940?

NCT02643940 is sponsored by Mid and South Essex NHS Foundation Trust.

What condition does NCT02643940 study?

NCT02643940 studies Acute Coronary Syndrome, Coronary Artery Disease.

Is NCT02643940 still recruiting?

NCT02643940 is currently completed. Last updated 11 January 2022.

Last reviewed 2022-01-11 · How we verify

NCT02643940: IMPACT-CTO

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Physiological Impact of CTO PCI on Coronary Pressure Measurements and Correlation in Donor Vessel

Completed Last updated 11 January 2022

What this trial tests

trial in Acute Coronary Syndrome in 42 participants. Completed in 31 May 2018.

Timeline

1 October 2015

Primary endpoint
31 May 2018

31 May 2018

Quick facts

Lead sponsor	Mid and South Essex NHS Foundation Trust
Status	Completed
Study type	OBSERVATIONAL
Enrollment	42
Start date	1 October 2015
Primary completion	31 May 2018
Estimated completion	31 May 2018
Sites	1 location across United Kingdom

Conditions studied

Acute Coronary Syndrome — all drugs for Acute Coronary Syndrome →
Coronary Artery Disease — all drugs for Coronary Artery Disease →

Sponsor

Mid and South Essex NHS Foundation Trust

Who can join

18 and older, any sex, with Acute Coronary Syndrome or Coronary Artery Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study will be recording pressure wire readings from both blocked and narrowed arteries, to better guide treatment options; medications, stents or potentially bypass surgery, for patients with Chronic Total Occlusion (CTO).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Stress perfusion cardiovascular magnetic resonance and serial fractional flow reserve assessment of the left anterior descending artery in patients undergoing right coronary artery chronic total occlusion revascularization.
Jones RE, Karamasis GV, Dungu JN, Mohdnazri SR, et al · · 2022 · cited 2× · PMID 32037503 · DOI 10.5603/cj.a2020.0007

Verify or expand the search:

Other recruiting trials for Acute Coronary Syndrome

Currently open trials in the same condition.

NCT06535568 — Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO · NA · recruiting
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NCT07032389 — A Polypill for Acute Coronary Syndrome · Phase 2 · recruiting
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NCT06416813 — Preventive Intervention Value of DCB in Vulnerable Coronary Atherosclerotic Plaques · NA · active not recruiting

Other Mid and South Essex NHS Foundation Trust trials

Trials by the same sponsor.

NCT06702306 — Duplex UltraSound afTer Endo Revascularisation - Feasibility Randomised Control Trial (DUSTER) · NA · active not recruiting
NCT07173426 — Bioimpedance Integration for Optimized Fluid Management in Decompensated Heart Failure · NA · recruiting
NCT06628115 — Post Market Study of Cerament V/G in Pedal Osteomyelitis · NA · not yet recruiting
NCT06247761 — STASSH - TRAUMA - Absorbable vs Non-Absorbable Sutures in Trauma Hand Surgery · NA · unknown
NCT05035771 — The IMPACT PAD Study · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02643940 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mid and South Essex NHS Foundation Trust
Last refreshed: 11 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02643940.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing