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NCT02629029

Multi-Modality Imaging for Head & Neck Cancer Free Flap Design Assessment

Terminated NA Last updated 16 December 2020
What this trial tests

NA trial testing Pre-op CTA with IV contrast in Head and Neck Neoplasms in 4 participants. Terminated before completion.

Timeline
30 May 2015
Primary endpoint
27 November 2020
27 November 2020

Quick facts

Lead sponsorUniversity Health Network, Toronto
PhaseNA
StatusTerminated
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment4
Start date30 May 2015
Primary completion27 November 2020
Estimated completion27 November 2020
Sites1 location across Canada

Drugs / interventions tested

Conditions studied

Sponsor

University Health Network, Toronto

Who can join

18 and older, any sex, with Head and Neck Neoplasms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Surgical reconstruction of anatomical structures after head and neck cancer resection has made enormous strides in the past 20 years with advancing flap techniques and the usage of perforating vessels, but accurate and consistent identification of these perforators has remained a challenge due to the varying anatomy of vasculature in the donor region. Computed tomography angiography (CTA) has been used increasingly in preoperative free flap perforator mapping for breast reconstruction but has been limited in head and neck applications. In addition, indocyanine green (ICG) assisted NIR fluorescence angiography has been developed for intra-operative flap assessment. In this study, the investigators propose to assess a previously undocumented, multi-modal imaging technique with preoperative dual energy CTA to design and intraoperative ICG assisted NIR angiography to assess free flap in head and neck reconstruction.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Fluorescence Guidance in Surgical Oncology: Challenges, Opportunities, and Translation.
    Olson MT, Ly QP, Mohs AM. · · 2019 · cited 48× · PMID 29942988 · DOI 10.1007/s11307-018-1239-2

Verify or expand the search:

Other recruiting trials for Head and Neck Neoplasms

Currently open trials in the same condition.

Other University Health Network, Toronto trials

Trials by the same sponsor.

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Data sources for this page

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