NCT02628548 is a NA clinical trial of Cognitive training program in Aging, sponsored by Massachusetts General Hospital.

Who is sponsoring NCT02628548?

NCT02628548 is sponsored by Massachusetts General Hospital.

What drugs are being tested in NCT02628548?

Interventions in NCT02628548: Cognitive training program.

Is NCT02628548 still recruiting?

NCT02628548 is currently completed. Last updated 7 September 2022.

Last reviewed 2022-09-07 · How we verify

NCT02628548

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Neural Correlates of Successful Cognitive Aging

Completed NA Last updated 7 September 2022

What this trial tests

NA trial testing Cognitive training program in Aging in 175 participants. Completed in 31 December 2021.

Timeline

18 January 2016

Primary endpoint
31 December 2021

31 December 2021

Quick facts

Lead sponsor	Massachusetts General Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	basic science
Enrollment	175
Start date	18 January 2016
Primary completion	31 December 2021
Estimated completion	31 December 2021
Sites	1 location across United States

Drugs / interventions tested

Cognitive training program

Conditions studied

Aging — all drugs for Aging →

Sponsor

Massachusetts General Hospital

Who can join

Adults 65 to 85, any sex, with Aging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Normal aging is associated with gradual cognitive declines. These mild neurocognitive disturbances affect daily functioning, health status, and quality of life, and likely account for the roughly $2.9 billion lost by the elderly each year to fraud. The goal of this project is to compare two different 8-week training programs to promote successful neural and cognitive aging. Changes in neural structure and cognitive function will be assessed in a cohort of older adults, as well as the long-term stability of these changes over 24 months.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Diabetes: a tipping point in neurodegenerative diseases.
Santiago JA, Karthikeyan M, Lackey M, Villavicencio D, et al · · 2023 · cited 41× · PMID 37827904 · DOI 10.1016/j.molmed.2023.09.005
Mindfulness Training Improves Cognition and Strengthens Intrinsic Connectivity Between the Hippocampus and Posteromedial Cortex in Healthy Older Adults.
Sevinc G, Rusche J, Wong B, Datta T, et al · · 2021 · cited 25× · PMID 34512305 · DOI 10.3389/fnagi.2021.702796

Verify or expand the search:

Other trials of Cognitive training program

Trials testing the same drug.

NCT03272711 — Remediation of Age-related Cognitive Decline: Vortioxetine and Cognitive Training · Phase 4 · completed

Other recruiting trials for Aging

Currently open trials in the same condition.

NCT02831335 — Technical Development of Multi-Parametric Renocerebral MRI · recruiting
NCT07099053 — Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging · recruiting
NCT07504068 — Effects of Physical Exercise and a Nutritional Supplement on Body Composition, Metabolic Function, and Overall Health in · NA · recruiting
NCT07525453 — Effects of Three Different Exercise Programs on Dynamic Balance in Community-Dwelling Older Adults · NA · recruiting
NCT07500727 — Skeletal Muscle Aging and Responsiveness in Aged People With MS · NA · recruiting

Other Massachusetts General Hospital trials

Trials by the same sponsor.

NCT03585946 — Outcomes in Stevens Johnsons Syndrome and Toxic Epidermal Necrolysis · withdrawn
NCT07214831 — A Feasibility and Acceptability Study of a Large Language Model-based Chatbot for Brief Alcohol Intervention Among Emerg · NA · not yet recruiting
NCT06686901 — A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior · NA · not yet recruiting
NCT05854212 — Behavioral Economics to Implement Nutrition Ranking in Food Pantries · NA · not yet recruiting
NCT07323446 — The MIND Study: The MGH/MIT Investigation of NAC on Dysregulation · EARLY_PHASE1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02628548 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Massachusetts General Hospital
Last refreshed: 7 September 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02628548.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing