Last reviewed · How we verify
NCT02625675
Using Thoracic Ultrasound to Predict Pleurodesis Success in Malignant Pleural Effusions: a Pilot Study
trial testing Ultrasound scan in Malignant Pleural Effusion in 18 participants. Completed in 6 July 2017.
6 July 2017
Quick facts
| Lead sponsor | University of Oxford |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 18 |
| Start date | 19 March 2015 |
| Primary completion | 6 July 2017 |
| Estimated completion | 6 July 2017 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Ultrasound scan
Conditions studied
- Malignant Pleural Effusion — all drugs for Malignant Pleural Effusion →
Sponsor
University of Oxford
Who can join
18 and older, any sex, with Malignant Pleural Effusion. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The observational pilot study at the Churchill Hospital, funded by Oxford Respiratory Trials Unit, will assess the feasibility and efficacy of thoracic ultrasound (TUS) assessment in patients undergoing talc pleurodesis via intercostal chest drain (ICD) for recurrent symptomatic malignant pleural effusions (MPE). Participants will undergo TUS pre and post pleurodesis on up to four occasions. We hypothesise that a TUS scoring system will be able to predict short and long-term pleurodesis success earlier than current conventional medical practice allows. This study may ultimately allow the proposal of a treatment algorithm to manage patients with MPE in a more efficient manner.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Thoracic Ultrasound as an Early Predictor of Pleurodesis Success in Malignant Pleural Effusion.
Corcoran JP, Hallifax RJ, Mercer RM, Yousuf A, et al · · 2018 · cited 16× · PMID 30243566 · DOI 10.1016/j.chest.2018.08.1031
Verify or expand the search:
- PubMed search for NCT02625675
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ultrasound scan
Trials testing the same drug.
- NCT04857476 — Do Patients With Skin Psoriasis Have Sub-clinical Features of Active Psoriatic Arthritis on Musculoskeletal UltraSound? · NA · terminated
- NCT04194736 — Evaluation of the Occurrence of Early Thrombosis on Central Venous Catheter by Ultrasound in Pediatric Intensive Care Un · NA · completed
- NCT04547270 — High Definition Ultrasound Imaging of the Intermuscular Bridges at the Interscalene Groove · completed
- NCT04127149 — Evaluation of Ultra-portable Ultrasound in General Practice · NA · completed
- NCT02946229 — Data Collection for Next Generation Ultrasound Technology Development · NA · completed
Other recruiting trials for Malignant Pleural Effusion
Currently open trials in the same condition.
- NCT06421610 — OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion. · Phase 1 · recruiting
- NCT05620329 — UNC Pleural Fluid Registry · recruiting
Other University of Oxford trials
Trials by the same sponsor.
- NCT05380388 — A Safety, Immunogenicity and Efficacy Study of PvRII/Matrix-M in Healthy Thai Adults Living in Thailand ( MIST3 ) · Phase 2 · not yet recruiting
- NCT07470424 — A Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults · Phase 1 · not yet recruiting
- NCT07345910 — Environment, Pathogens, and Host Interactions in Melioidosis · not yet recruiting
- NCT07434973 — Stratification and Treatment in Early Psychosis Study - PROMOTE · Phase 3 · not yet recruiting
- NCT07460401 — 'Do Patient Characteristics Associate With Poor Outcome With Femoral Acetabular Impingement Syndrome (FAIS) Following Ph · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02625675 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Oxford
- Last refreshed: 9 January 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02625675.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing