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NCT02625675

Using Thoracic Ultrasound to Predict Pleurodesis Success in Malignant Pleural Effusions: a Pilot Study

Completed Last updated 9 January 2018
What this trial tests

trial testing Ultrasound scan in Malignant Pleural Effusion in 18 participants. Completed in 6 July 2017.

Timeline
19 March 2015
Primary endpoint
6 July 2017
6 July 2017

Quick facts

Lead sponsorUniversity of Oxford
StatusCompleted
Study typeOBSERVATIONAL
Enrollment18
Start date19 March 2015
Primary completion6 July 2017
Estimated completion6 July 2017
Sites1 location across United Kingdom

Drugs / interventions tested

Conditions studied

Sponsor

University of Oxford

Who can join

18 and older, any sex, with Malignant Pleural Effusion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The observational pilot study at the Churchill Hospital, funded by Oxford Respiratory Trials Unit, will assess the feasibility and efficacy of thoracic ultrasound (TUS) assessment in patients undergoing talc pleurodesis via intercostal chest drain (ICD) for recurrent symptomatic malignant pleural effusions (MPE). Participants will undergo TUS pre and post pleurodesis on up to four occasions. We hypothesise that a TUS scoring system will be able to predict short and long-term pleurodesis success earlier than current conventional medical practice allows. This study may ultimately allow the proposal of a treatment algorithm to manage patients with MPE in a more efficient manner.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Thoracic Ultrasound as an Early Predictor of Pleurodesis Success in Malignant Pleural Effusion.
    Corcoran JP, Hallifax RJ, Mercer RM, Yousuf A, et al · · 2018 · cited 16× · PMID 30243566 · DOI 10.1016/j.chest.2018.08.1031

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Other trials of Ultrasound scan

Trials testing the same drug.

Other recruiting trials for Malignant Pleural Effusion

Currently open trials in the same condition.

Other University of Oxford trials

Trials by the same sponsor.

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