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NCT02623881
Cervical Pessary vs. Vaginal Progesterone for Preventing Premature Birth in IVF Twin Pregnancies
Completed
NA
Last updated 22 December 2017
What this trial tests
NA trial testing Cervical pessary in Pregnancy in 300 participants. Completed in 2 November 2017.
Timeline
4 March 2016
Primary endpoint
2 November 2017
2 November 2017
2 November 2017
Quick facts
| Lead sponsor | Vietnam National University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 300 |
| Start date | 4 March 2016 |
| Primary completion | 2 November 2017 |
| Estimated completion | 2 November 2017 |
| Sites | 1 location across Vietnam |
Drugs / interventions tested
- Cervical pessary
- Vaginal progesterone — full drug profile →
Conditions studied
- Pregnancy — all drugs for Pregnancy →
Sponsor
Vietnam National University
Who can join
18 and older, female only, with Pregnancy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To compare the effectiveness of cervical pessary (Arabin) and vaginal progesterone for preventing premature birth in twin pregnancies after IVF
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
-
Pessary Compared With Vaginal Progesterone for the Prevention of Preterm Birth in Women With Twin Pregnancies and Cervical Length Less Than 38 mm: A Randomized Controlled Trial.
Dang VQ, Nguyen LK, Pham TD, He YTN, et al · · 2019 · cited 31× · PMID 30741812 · DOI 10.1097/aog.0000000000003136 -
Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple pregnancy.
Dodd JM, Grivell RM, OBrien CM, Dowswell T, et al · · 2017 · cited 25× · PMID 29086920 · DOI 10.1002/14651858.cd012024.pub2 -
Controversies about the Secondary Prevention of Spontaneous Preterm Birth.
Kyvernitakis I, Maul H, Bahlmann F. · · 2018 · cited 16× · PMID 29962517 · DOI 10.1055/a-0611-5337 -
Prenatal administration of progestogens for preventing spontaneous preterm birth in women with a multiple pregnancy.
Dodd JM, Grivell RM, OBrien CM, Dowswell T, et al · · 2019 · cited 14× · PMID 31745984 · DOI 10.1002/14651858.cd012024.pub3 -
Development of children born to women with twin pregnancies treated with cervical pessary or vaginal progesterone: Follow-up of a randomized controlled trial.
Tran VTT, Nguyen NA, Nguyen NT, Vo TTM, et al · · 2023 · cited 5× · PMID 36905390 · DOI 10.1111/aogs.14545 -
Long-term development of children born to women with twin pregnancies treated with cervical pessary or vaginal progesterone: follow-up of a randomized controlled trial
Tran V, Nguyen N, Nguyen N, Vo T, et al · · 2024 · DOI 10.22541/au.170669485.50507524/v1
Verify or expand the search:
- PubMed search for NCT02623881
- Europe PMC full search
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Related trials
Other trials of Cervical pessary
Trials testing the same drug.
- NCT04300322 — Pessary Versus Progesterone in Singletons · NA · unknown
- NCT04147117 — Cervical Pessary to Prevent Preterm Singleton Birth in High Risk Population · NA · unknown
- NCT02678026 — Pessary as Adjunctive Therapy to Cerclage for the Prevention of Preterm Birth · Phase 3 · withdrawn
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Currently open trials in the same condition.
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Other Vietnam National University trials
Trials by the same sponsor.
- NCT03181243 — The Acceptance, Safety, and Efficacy of MadaJet Versus Needle Injection for Sperm Retrieval in Patients With Azoospermia · NA · completed
- NCT03174691 — Early Luteal Progesterone Profile in IVF Patients Triggered With hCG · NA · completed
- NCT02471573 — Freeze All Protocol Versus Fresh Embryo Transfer in Women Undergoing In-vitro Fertilization (IVF) · NA · completed
- NCT02466204 — Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
Data sources for this page
- Trial protocol + status: ClinicalTrials.gov NCT02623881 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Vietnam National University
- Last refreshed: 22 December 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02623881.
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