Who is sponsoring DEXsedation?

DEXsedation is sponsored by Assiut University.

What drugs are being tested in DEXsedation?

Interventions: Dexmedetomidine, Propofol.

What is the status of DEXsedation?

DEXsedation is currently COMPLETED.

Last reviewed 2016-08-20 · How we verify

Dexmedetomidine Versus Propofol for Prolonged Sedation in Poly Traumatized Mechanically Ventilated Patients (DEXsedation)

NCT02606409 Phase 2/Phase 3 COMPLETED

Dexmedetomidine, a central and peripheral α2-receptor agonist distinct from GABA receptor for benzodiazepines and propofol, has been approved by the US Food and Drug Administration only for use up to 24 h in mechanically ventilated patients. The investigators aim to compare dexmedetomidine with propofol for sedation \>24h in poly traumatized mechanically ventilated patients.

Details

Lead sponsor	Assiut University
Phase	Phase 2/Phase 3
Status	COMPLETED
Enrolment	60
Start date	2015-11
Completion	2016-06

Conditions

Trauma

Interventions

Dexmedetomidine
Propofol

Primary outcomes

percentage of time with in the target sedation range of Richmond Agitation Sedation Scale-3-0 — 3 days
sedation goal is to maintain Richmond Agitation Sedation Scale from -3 up to 0

Countries

Egypt