Who is sponsoring ECOGREFFE-B?

ECOGREFFE-B is sponsored by Hospices Civils de Lyon.

What condition does ECOGREFFE-B study?

ECOGREFFE-B studies Liver Transplantation.

What drugs are being tested in ECOGREFFE-B?

Interventions: cccDNA assay on liver biopsy.

What is the status of ECOGREFFE-B?

ECOGREFFE-B is currently COMPLETED.

Last reviewed 2019-01-10 · How we verify

Study of cccDNA in Liver Transplant Patients With B Virus Markers (ECOGREFFE-B)

NCT02602847 COMPLETED

The aim of this study is to validate in the context of liver transplantation, the interest of the cccDNA assay technique developed by the team of Professor Zoulim (INSERM U1052) on liver biopsy and correlate this assay cccDNA in hepatitis B virus (HBV) viral load and serum liver through several groups of patients at transplantation (on graft and native liver explant) and after transplantation.

Details

Lead sponsor	Hospices Civils de Lyon
Status	COMPLETED
Enrolment	40
Start date	2012-11
Completion	2018-11

Conditions

Liver Transplantation

Interventions

cccDNA assay on liver biopsy

Primary outcomes

cccDNA rate on native explant and liver transplant during transplantation and on liver biopsy — 1 year after transplantation
cccDNA rate will be assessed on native explant and liver transplant during transplantation and on liver biopsy (between M1 to M3 and 12 months (M12) after transplantation) to study the colonization of new hepatocytes by HBV

Countries

France