NCT02599246 (NIVLEAKS) is a clinical trial in COPD, sponsored by Breas Medical S.A.R.L..

Who is sponsoring NCT02599246?

NCT02599246 is sponsored by Breas Medical S.A.R.L..

What condition does NCT02599246 study?

NCT02599246 studies COPD, Home Care, Oxygen Therapy.

Is NCT02599246 still recruiting?

NCT02599246 is currently completed. Last updated 1 February 2017.

Last reviewed 2017-02-01 · How we verify

NCT02599246: NIVLEAKS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

FiO2 in Chronic Obstructive Pulmonary Disease (COPD) Patient Normobaric O2 Versus NIV

Completed Last updated 1 February 2017

What this trial tests

trial in COPD in 14 participants. Completed in 24 February 2016.

Timeline

17 November 2015

Primary endpoint
22 February 2016

24 February 2016

Quick facts

Lead sponsor	Breas Medical S.A.R.L.
Status	Completed
Study type	OBSERVATIONAL
Enrollment	14
Start date	17 November 2015
Primary completion	22 February 2016
Estimated completion	24 February 2016
Sites	1 location across France

Conditions studied

COPD — all drugs for COPD →
Home Care — all drugs for Home Care →
Oxygen Therapy — all drugs for Oxygen Therapy →

Sponsor

Breas Medical S.A.R.L.

Who can join

18 and older, any sex, with COPD or Home Care. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to compare pharyngeal FiO2 in day time with nasal normobaric O2 with inhaled FiO2 in the night time with home care ventilator NIV at the same O2 flow.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

In COPD, Nocturnal Noninvasive Ventilation Reduces the FIO2 Delivered Compared With Long-Term Oxygen Therapy at the Same Flow.
Cardinale M, Cungi PJ, Esnault P, Castagna O, et al · · 2020 · cited 4× · PMID 32694183 · DOI 10.4187/respcare.07570

Verify or expand the search:

Other recruiting trials for COPD

Currently open trials in the same condition.

NCT07344649 — Turkish Validation of the Nijmegen Questionnaire in COPD · recruiting
NCT07524023 — Emotional-distress-based Integrated Care Programme in Patients With Stable COPD · NA · recruiting
NCT07460154 — Structured Review: To Optimise Management and Prevent Harm in COPD · NA · recruiting
NCT07462221 — Effect of Telenursing on Oral Health · NA · recruiting
NCT07051707 — Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02599246 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Breas Medical S.A.R.L.
Last refreshed: 1 February 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02599246.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing