NCT02575235 (CPC2) is a EARLY_PHASE1 clinical trial of Cetylpyridinium Chloride (CPC) in Sarcopenia, sponsored by Seoul National University Hospital.

Who is sponsoring NCT02575235?

NCT02575235 is sponsored by Seoul National University Hospital.

What drugs are being tested in NCT02575235?

Interventions in NCT02575235: Cetylpyridinium Chloride (CPC), placebo.

What condition does NCT02575235 study?

NCT02575235 studies Sarcopenia.

Is NCT02575235 still recruiting?

NCT02575235 is currently completed. Last updated 8 October 2021.

Last reviewed 2021-10-08 · How we verify

NCT02575235: CPC2

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Trial to Assess the Preventive Effects of Cetylpyridinium Chloride on Sarcopenia

Completed EARLY_PHASE1 Last updated 8 October 2021

What this trial tests

EARLY_PHASE1 trial testing Cetylpyridinium Chloride (CPC) in Sarcopenia in 100 participants. Completed in 1 July 2016.

Timeline

1 October 2015

Primary endpoint
1 July 2016

1 July 2016

Quick facts

Lead sponsor	Seoul National University Hospital
Phase	EARLY_PHASE1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	100
Start date	1 October 2015
Primary completion	1 July 2016
Estimated completion	1 July 2016
Sites	1 location across South Korea

Drugs / interventions tested

Cetylpyridinium Chloride (CPC) — full drug profile →
placebo

Conditions studied

Sarcopenia — all drugs for Sarcopenia →

Sponsor

Seoul National University Hospital

Who can join

60 and older, any sex, with Sarcopenia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study is to assess the impact on the prevention of sarcopenia after taking cetylpyridinium chloride targeting the patients of pre-sarcopenia or sarcopenia over the age of 60

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

Update on the ESCEO recommendation for the conduct of clinical trials for drugs aiming at the treatment of sarcopenia in older adults.
Reginster JY, Beaudart C, Al-Daghri N, Avouac B, et al · · 2021 · cited 60× · PMID 32737844 · DOI 10.1007/s40520-020-01663-4
The biphasic and age-dependent impact of klotho on hallmarks of aging and skeletal muscle function.
Clemens Z, Sivakumar S, Pius A, Sahu A, et al · · 2021 · cited 43× · PMID 33876724 · DOI 10.7554/elife.61138
Targeting Crosstalk of Signaling Pathways among Muscles-Bone-Adipose Tissue: A Promising Therapeutic Approach for Sarcopenia.
Sharma AR, Chatterjee S, Lee YH, Lee SS. · · 2024 · cited 10× · PMID 37815907 · DOI 10.14336/ad.2023.00903
Receptor-Mediated Muscle Homeostasis as a Target for Sarcopenia Therapeutics.
Yoon JH, Kwon KS. · · 2021 · cited 8× · PMID 34218646 · DOI 10.3803/enm.2021.1081
Sarcopenia and Muscle Aging: Updated Insights into Molecular Mechanisms and Translational Therapeutics.
Nguyen TT, Dao T, Nguyen HT, Park JH, et al · · 2026 · cited 1× · PMID 41674227 · DOI 10.3803/enm.2025.2656
Development of pharmacological interventions for the treatment of sarcopenia.
Yang D, Su L, Zhang L, Li Y, et al · · 2026 · PMID 42164047 · DOI 10.21037/atm-2025-1-184

Verify or expand the search:

Other trials of Cetylpyridinium Chloride (CPC)

Trials testing the same drug.

NCT06607172 — Clinical Efficacy of the Combined Effect of Oral Irrigator and Chemicals (0.075% CPC) · Phase 3 · completed
NCT07211061 — A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods · Phase 4 · completed

Other recruiting trials for Sarcopenia

Currently open trials in the same condition.

NCT07500376 — Multimodal Nutritional and Sarcopenia Assessment for Risk Stratification in Lung Cancer Surgery · recruiting
NCT07456956 — HIIT vs MCIT for Stroke-Related Sarcopenia in Ischemic Stroke · NA · recruiting
NCT07398495 — Multimodal Training Effects in Middle-Aged and Older Adults With Diabetic Sarcopenia · NA · recruiting
NCT07494916 — Effects of Functional Task Training on Muscle Health and Function in Older Adults With Sarcopenia · NA · active not recruiting
NCT07426159 — AI-Guided Sarcopenia Risk Assessment and Detection · NA · active not recruiting

Other Seoul National University Hospital trials

Trials by the same sponsor.

NCT07262944 — EOI Block in Otoplasty With Rib Cartilage Graft · NA · recruiting
NCT07464210 — Nemtabrutinib, Bortezomib, and Rituximab for WM · Phase 2 · not yet recruiting
NCT07550803 — Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery · NA · not yet recruiting
NCT07522138 — Home-based Self-exercise in Patients With Parkinson's Disease: A Feasibility Study · NA · not yet recruiting
NCT07476651 — Scout Dose of Resin Microspheres · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02575235 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
Last refreshed: 8 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02575235.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing