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NCT02566746: ConstiCAPE
Contribution of Percutaneous Endoscopic Caecostomie in the Management of Severe Constipation Refractory to Medical Treatment
NA trial testing Chait Trapdoor caecostomie catheter in Constipation in 28 participants. Completed in 23 June 2022.
23 June 2022
Quick facts
| Lead sponsor | Nantes University Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 28 |
| Start date | 20 June 2016 |
| Primary completion | 23 June 2022 |
| Estimated completion | 23 June 2022 |
| Sites | 3 locations across France |
Drugs / interventions tested
- Chait Trapdoor caecostomie catheter
- continuation of optimal medical therapy — full drug profile →
Conditions studied
- Constipation — all drugs for Constipation →
Sponsor
Nantes University Hospital
Who can join
Adults 18 to 75, any sex, with Constipation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators' study aims to compare the results of percutaneous endoscopic caecostomie (CPE) to optimal medical therapy in the treatment of patients with constipation refractory to medical treatment. The primary endpoint will be the quality of life assessed by the Gastrointestinal Quality Of Life Index (GIQLI) at one year. The secondary endpoints are digestive symptoms, Kess's constipation scores and Cleveland's incontinence score, tolerance of the Chait TrapdoorTM caecostomy catheter (CTCC) and the collection of possible complications. The patients included must meet the classification criteria of Rome III, have an elongated colonic transit time, have had a complete colonoscopy and be refractory to medical treatment including at least one stimulant laxative or suppositories or enemas retrograde.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Region-specific remodeling of the enteric nervous system and enteroendocrine cells in the colon of spinal cord injury patients.
Lefèvre C, Le Roy C, Bessard A, Le Berre-Scoul C, et al · · 2023 · cited 9× · PMID 37803037 · DOI 10.1038/s41598-023-44057-y
Verify or expand the search:
- PubMed search for NCT02566746
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Constipation
Currently open trials in the same condition.
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- NCT07135362 — The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement · NA · recruiting
- NCT07091084 — A Study of Herbal Supplements in Cancer Survivors With Constipation · NA · recruiting
Other Nantes University Hospital trials
Trials by the same sponsor.
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- NCT07467382 — GOAT (Gait Observation of Achilles Tendon) · not yet recruiting
- NCT07490379 — Comparison of the Efficacy of Transcranial Direct Current Stimulation at Home Versus in Hospital Settings in Patients Wi · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02566746 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nantes University Hospital
- Last refreshed: 27 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02566746.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing