Comparison of Glycaemic Fluctuation and Oxidative Stress Between Two Short-term Therapies for Type 2 Diabetes (COGFOST)

NCT02526810 Phase 4 UNKNOWN

The purpose of this study is to compare the blood glucose control, glycaemic fluctuation and oxidative stress for Type 2 Diabetes between two therapies, one is glargine combined with oral drugs and the other is continuous subcutaneous insulin injection.

Details

Lead sponsor	Third Affiliated Hospital, Sun Yat-Sen University
Phase	Phase 4
Status	UNKNOWN
Enrolment	70
Start date	2015-07
Completion	2016-09

Conditions

• Diabetes Mellitus, Type 2

Interventions

• insulin lispro
• Insulin Glargine

Primary outcomes

• mean amplitude of glycemic excursions( MAGE) — 3-5 days after patients achieving the target glucose levels, From date of randomization, assessed up to 10 days
  a Medtronic dynamic blood glucose meter was applied to the patient for 72 hours, and MAGE is calculated according to the data.

Countries

China