A Prospective Randomized Controlled Clinical Trial of Patient Controlled Epidural Analgesia Versus Intravenous Patient Controlled Analgesia for Post-Operative Pain Control in Patients Undergoing Elective Open Liver Resection

NCT02523443 Phase 3 ACTIVE_NOT_RECRUITING

The purpose of this study is to learn whether patient-controlled epidural analgesia (PCEA) is a better method for managing pain after liver resection compared to patient-controlled analgesia (IV PCA). Currently, the standard pain control method for liver resection patients is IV PCA. There is not enough data on how epidural (PCEA) relieves pain and movement on a day to day basis after liver resection.

Details

Lead sponsor	Memorial Sloan Kettering Cancer Center
Phase	Phase 3
Status	ACTIVE_NOT_RECRUITING
Enrolment	231
Start date	2015-08
Completion	2026-08

Conditions

• Liver Cancer
• Pain Management

Interventions

• IV PCA
• PCEA

Primary outcomes

• ability to detect a 2-point NRS scale difference — 1 year
  The primary endpoint assesses differences in pain control between PCEA and IV PCA after a "get up and go" test performed on POD2 during pain rounds, evaluated using a NRS pain score.

Countries

United States