NCT02519881 is a NA clinical trial of Microfracture in Defect of Articular Cartilage, sponsored by Cellontech Co., Ltd..

Who is sponsoring NCT02519881?

NCT02519881 is sponsored by Cellontech Co., Ltd..

What drugs are being tested in NCT02519881?

Interventions in NCT02519881: Microfracture, CartiFill.

What condition does NCT02519881 study?

NCT02519881 studies Defect of Articular Cartilage.

Is NCT02519881 still recruiting?

NCT02519881 is currently completed. Last updated 7 April 2026.

Last reviewed 2026-04-07 · How we verify

NCT02519881

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

the Efficacy and Safety of a Modified Microfracture Using Collagen Compared to Those of a Simple Microfracture in Ankle

Completed NA Last updated 7 April 2026

What this trial tests

NA trial testing Microfracture in Defect of Articular Cartilage in 60 participants. Completed in 23 January 2018.

Timeline

17 February 2014

Primary endpoint
23 January 2018

23 January 2018

Quick facts

Lead sponsor	Cellontech Co., Ltd.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Primary purpose	treatment
Enrollment	60
Start date	17 February 2014
Primary completion	23 January 2018
Estimated completion	23 January 2018
Sites	3 locations across South Korea

Drugs / interventions tested

Microfracture
CartiFill

Conditions studied

Defect of Articular Cartilage — all drugs for Defect of Articular Cartilage →

Sponsor

Cellontech Co., Ltd. — full company profile →

Who can join

15 and older, any sex, with Defect of Articular Cartilage. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study was designed to evaluate the efficacy and safety of a modified microfracture using collagen, and to compare them with those of a simple microfracture in patients with cartilage defects in their ankles.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

An Update on the Clinical Efficacy and Safety of Collagen Injectables for Aesthetic and Regenerative Medicine Applications.
Salvatore L, Natali ML, Brunetti C, Sannino A, et al · · 2023 · cited 39× · PMID 36850304 · DOI 10.3390/polym15041020
Arthroscopic microfracture with atelocollagen augmentation for osteochondral lesion of the talus: a multicenter randomized controlled trial.
Lee YK, Young KW, Kim JS, Lee HS, et al · · 2020 · cited 20× · PMID 33143647 · DOI 10.1186/s12891-020-03730-3
Current Advances in the Regeneration of Degenerated Articular Cartilage: A Literature Review on Tissue Engineering and Its Recent Clinical Translation.
Daou F, Cochis A, Leigheb M, Rimondini L. · · 2021 · cited 17× · PMID 35009175 · DOI 10.3390/ma15010031

Verify or expand the search:

Other trials of Microfracture

Trials testing the same drug.

NCT06249828 — Clinical Trial to Evaluate the Efficacy and Safety of MegaCarti® in Knee Cartilage Defects · NA · completed
NCT05799196 — The Effectiveness of the Microfracture Technique in the Meniscal Healing · unknown
NCT05785949 — Chondro-Gide® Bilayer Collagen Membrane in Knee Cartilage Defect Repair · NA · terminated
NCT04953572 — Treatment of Cartilage Defects With Peripheral Blood Stem Cells · Phase 1 · unknown
NCT04537013 — Clinical Study of Chondro-Gide® for Large Chondral Lesions in the Knee · NA · terminated

Other Cellontech Co., Ltd. trials

Trials by the same sponsor.

NCT07511777 — Clinical Trial to Assess the Safety and Efficacy of Intra-articular Injection Collagen Versus Hyaluronic Acid on Knee Os · NA · completed
NCT02539082 — the Safety and Efficacy of Collagen Injection in Patients With Plantar Fasciitis · NA · completed
NCT02539069 — The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy · NA · completed
NCT02539056 — The Post-marketing Surveillance to Evaluate the Efficacy and Safety of a CHONDRON (Autologous Cultured Chondrocyte) · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02519881 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cellontech Co., Ltd.
Last refreshed: 7 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02519881.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing