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NCT02513589: PLAQINSTEP

Molecular Imaging of Inflammation With 18F-PBR06 to Identify Unstable Carotid Plaques in Patients With Stroke

Terminated Phase 2 Last updated 23 November 2018
What this trial tests

Phase 2 trial testing 18F-PBR06 in Stroke in 3 participants. Terminated before completion.

Timeline
18 September 2017
Primary endpoint
4 July 2018
4 July 2018

Quick facts

Lead sponsorUniversity Hospital, Bordeaux
PhasePhase 2
StatusTerminated
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment3
Start date18 September 2017
Primary completion4 July 2018
Estimated completion4 July 2018
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Bordeaux

Who can join

18 and older, male only, with Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Evaluating an innovative molecular imaging technique to visualize inflammation of the atherosclerotic plaque in patients with a recent ischemic stroke (\<15 days) with carotid stenosis\> 50%, by performing a Positron emission tomography-computed tomography (PET-CT) with PBR06 18F, a tracer for Translocator protein (TPSO).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. In vitro and pilot in vivo imaging of 18 kDa translocator protein (TSPO) in inflammatory vascular disease.
    Schollhammer R, Lepreux S, Barthe N, Vimont D, et al · · 2021 · cited 10× · PMID 33950298 · DOI 10.1186/s13550-021-00786-7

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Other trials of 18F-PBR06

Trials testing the same drug.

Other recruiting trials for Stroke

Currently open trials in the same condition.

Other University Hospital, Bordeaux trials

Trials by the same sponsor.

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Data sources for this page

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