Who is sponsoring REVERENT?

REVERENT is sponsored by Istituto Auxologico Italiano.

What condition does REVERENT study?

REVERENT studies Hypertension, High Blood Pressure Variability.

What drugs are being tested in REVERENT?

Interventions: Nifedipine GITS, Ramipril.

What is the status of REVERENT?

REVERENT is currently COMPLETED.

Last reviewed 2021-09-29 · How we verify

Short - Medium and Long Term Blood Pressure Variability in Essential Hypertensive Patients Treated With Nifedipine GITS or Ramipril - a Randomized Trial (REVERENT)

NCT02499822 Phase 4 COMPLETED

The purpose of this study is 1. to compare the effects of nifedipine GITS and ramipril on blood pressure variability in subjects with elevated blood pressure variability. 2. to assess whether the degree of treatment-induced changes in blood pressure variability, is related to the degree of regression (or progression) of organ damage in heart, kidneys and carotid arteries.

Details

Lead sponsor	Istituto Auxologico Italiano
Phase	Phase 4
Status	COMPLETED
Enrolment	168
Start date	2015-10
Completion	2020-11-01

Conditions

Hypertension
High Blood Pressure Variability

Interventions

Nifedipine GITS
Ramipril

Primary outcomes

Variability (standard deviation) of home systolic blood pressure at final visit — After 10 weeks of study treatment

Countries

China, Greece, Italy