Who is sponsoring NCT02488954?

NCT02488954 is sponsored by Rennes University Hospital.

What drugs are being tested in NCT02488954?

Interventions in NCT02488954: Probiotics in the form of cheese portion.

What condition does NCT02488954 study?

NCT02488954 studies Ulcerative Colitis.

Is NCT02488954 still recruiting?

NCT02488954 is currently terminated. Last updated 6 July 2017.

Last reviewed 2017-07-06 · How we verify

NCT02488954: EMMENTAL

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Interest of Propionibacterium Freudenreichii for the Treatment of Mild to Moderate Ulcerative Colitis

Terminated NA Last updated 6 July 2017

What this trial tests

NA trial testing Probiotics in the form of cheese portion in Ulcerative Colitis in 7 participants. Terminated before completion.

Timeline

12 February 2016

Primary endpoint
30 June 2017

30 June 2017

Quick facts

Lead sponsor	Rennes University Hospital
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	7
Start date	12 February 2016
Primary completion	30 June 2017
Estimated completion	30 June 2017
Sites	1 location across France

Drugs / interventions tested

Probiotics in the form of cheese portion

Conditions studied

Ulcerative Colitis — all drugs for Ulcerative Colitis →

Sponsor

Rennes University Hospital

Who can join

18 and older, any sex, with Ulcerative Colitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ulcerative colitis (UC) is an immune mediated chronic inflammatory bowel disease that results at least in part of an abnormal immune response to environmental factors including the intestinal microbiota. Thus, use of probiotics (microorganisms that are believed to provide health benefits when consume) may restore the gastrointestinal microbiota and reduce intestinal inflammation. Propionibacterium freudenreichii is used for the production of fermented food products (cheese). Some selected strains have strong anti-inflammatory properties. Use of cheese based on a monoxenic culture of anti-inflammatory strain of Propionibacterium freudenreichii may decrease disease activity during ulcerative colitis.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Natural compounds as safe therapeutic options for ulcerative colitis.
Gupta M, Mishra V, Gulati M, Kapoor B, et al · · 2022 · cited 55× · PMID 35212849 · DOI 10.1007/s10787-022-00931-1
Bile Salt Hydrolase-Competent Probiotics in the Management of IBD: Unlocking the "Bile Acid Code".
Gadaleta RM, Cariello M, Crudele L, Moschetta A. · · 2022 · cited 39× · PMID 35956388 · DOI 10.3390/nu14153212
Engineered Probiotic-Based Biomaterials for Inflammatory Bowel Disease Treatment.
Sang G, Wang B, Xie Y, Chen Y, et al · · 2025 · cited 9× · PMID 40093907 · DOI 10.7150/thno.103983

Verify or expand the search:

Other recruiting trials for Ulcerative Colitis

Currently open trials in the same condition.

NCT07185009 — A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Acti · Phase 3 · recruiting
NCT07265570 — Study Evaluating ISM5411 Administered Orally to Subjects With Active Ulcerative Colitis (BETHESDA) · Phase 2 · recruiting
NCT07223424 — Patient Preference for Subcutaneous vs. Intravenous Immune Therapy · Phase 2 · recruiting
NCT06405087 — A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD · Phase 3 · recruiting
NCT07184996 — An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Activ · Phase 3 · recruiting

Other Rennes University Hospital trials

Trials by the same sponsor.

NCT07527949 — PASTRAMI : Patient-specific Statistics for Microstructure-augmented Connectomics · NA · not yet recruiting
NCT07449832 — Sperm Epigenome in Hodgkin Lymphoma · NA · not yet recruiting
NCT06950398 — Normothermic Oxygenated Perfusion (NMP) Viability Testing Before Transplantation of Discarded Livers · Phase 2 · not yet recruiting
NCT07188753 — Randomized Controlled Trial Testing the Efficacy of Transcranial Magnetic Stimulation by Accelerated & High-dose Theta-b · NA · not yet recruiting
NCT06898099 — Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02488954 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Rennes University Hospital
Last refreshed: 6 July 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02488954.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing