Last reviewed · How we verify
NCT02481817: NoAAC PR-02
Treatment Alternatives in iSGS (NoAAC PR-02 Study)
trial testing Endoscopic dilation of subglottic stenosis in Idiopathic Subglottic Stenosis (iSGS) in 1,239 participants. Completed in 10 September 2020.
10 September 2020
Quick facts
| Lead sponsor | Vanderbilt University Medical Center |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,239 |
| Start date | 28 August 2015 |
| Primary completion | 10 September 2020 |
| Estimated completion | 10 September 2020 |
| Sites | 42 locations across United Kingdom, United States, Australia, Iceland |
Drugs / interventions tested
- Endoscopic dilation of subglottic stenosis
- Endoscopic resection of the stenosis
- Tracheal Resection
Conditions studied
- Idiopathic Subglottic Stenosis (iSGS) — all drugs for Idiopathic Subglottic Stenosis (iSGS) →
Sponsor
Vanderbilt University Medical Center
Who can join
18 and older, any sex, with Idiopathic Subglottic Stenosis (iSGS). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study is aimed at answering the questions; (1) How well do the most commonly used treatments in iSGS work? and (2) What quality-of-life trade-offs are associated with each approach? With the results of this trial, the investigators hope to provide information to iSGS patients: (1) Given my personal characteristics, conditions, and preferences, what should I expect will happen to me? and (2) What are my options, and what are the potential benefits and harms of these options?
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Treatment options in idiopathic subglottic stenosis: protocol for a prospective international multicentre pragmatic trial.
Gelbard A, Shyr Y, Berry L, Hillel AT, et al · · 2018 · cited 42× · PMID 29643170 · DOI 10.1136/bmjopen-2018-022243
Verify or expand the search:
- PubMed search for NCT02481817
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02481817 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Vanderbilt University Medical Center
- Last refreshed: 28 October 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02481817.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing