Last reviewed · How we verify
NCT02472171
Suppression of Postprandial Monocyte Activation by Fruit Rich in Anti-inflammatory Polyphenols or Docosahexaenoic Acid in Humans
NA trial testing High saturated fat meal, placebo powder and sunflower oil in Inflammation in 62 participants. Completed in 1 November 2017.
1 November 2017
Quick facts
| Lead sponsor | USDA, Western Human Nutrition Research Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 62 |
| Start date | 1 June 2015 |
| Primary completion | 1 November 2017 |
| Estimated completion | 1 November 2017 |
| Sites | 1 location across United States |
Drugs / interventions tested
- High saturated fat meal, placebo powder and sunflower oil
- High saturated fat meal, blueberry powder and sunflower oil
- High saturated fat meal, placebo powder and DHA
Conditions studied
- Inflammation — all drugs for Inflammation →
Sponsor
USDA, Western Human Nutrition Research Center — full company profile →
Who can join
Adults 18 to 60, any sex, with Inflammation. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Change in Monocyte activation in whole blood
Time frame: Measured at 0, 1, 3, and 6 hours after high fat meal with blueberries, DHA or placebo
Change in monocyte activation using monocyte activation assay in whole blood.
Sponsor's own description
The overall goal of the research study is to determine whether a high-fat meal causes postprandial (after meal) inflammation, and whether eating n-3 polyunsaturated fatty acids (PUFAs) or blueberries that are rich in anti-inflammatory polyphenols suppress the inflammation in healthy people.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Endotoxin May Not Be the Major Cause of Postprandial Inflammation in Adults Who Consume a Single High-Fat or Moderately High-Fat Meal.
Mo Z, Huang S, Burnett DJ, Rutledge JC, et al · · 2020 · cited 11× · PMID 32040591 · DOI 10.1093/jn/nxaa003
Verify or expand the search:
- PubMed search for NCT02472171
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other USDA, Western Human Nutrition Research Center trials
Trials by the same sponsor.
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- NCT05792137 — Postprandial Monocyte Study · NA · completed
- NCT05931471 — Yogurt and GI Health · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02472171 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by USDA, Western Human Nutrition Research Center
- Last refreshed: 26 October 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02472171.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing