Who is sponsoring Gelaring?

Gelaring is sponsored by Kratochvil Milan, MD.

What condition does Gelaring study?

Gelaring studies Hemorrhage, Surgical, Hip Replacement, Total, Thrombocytopathy.

What drugs are being tested in Gelaring?

Interventions: Gelofusine® B. Braun, Ringerfundin ® B. Braun.

Last reviewed 2015-06-02 · How we verify

Comparison of the Effects of Gelatine (Gelofusine ® B. Braun) Versus Crystalloid Solution (Ringerfundin ® B. Braun) for Volume Therapy on Coagulation, Thrombocyte Function and Thrombelastometry (ROTEM ®), in Elective Hip Replacement Surgery (Gelaring)

NCT02461329 NA UNKNOWN

The purpose of the study is to determine whether volume therapy with a solution of gelatine has negative impact on coagulation, platelet function, renal function in comparison with crystaloid solution (Ringerfundin).

Details

Lead sponsor	Kratochvil Milan, MD
Phase	NA
Status	UNKNOWN
Enrolment	50
Start date	2015-05
Completion	2016-12

Conditions

Hemorrhage, Surgical
Hip Replacement, Total
Thrombocytopathy

Interventions

Gelofusine® B. Braun
Ringerfundin ® B. Braun

Primary outcomes

Change of coagulation status and platelet function — perioperative, an expected average of 2 hours
Before and after the surgery (in OR) the investigator will obtain a blood sample from subject, standard coagulation test will be performed (INR, PT, aPTT, thrombin time), the investigator will perform ROTEM tests: EXTEM, INTEM and FIBTEM assay and blood sample will be tested for thrombocyte function - aggregation with ADP, collagen, epinephrine, TRAP - thrombin receptor-activated peptide.