Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation

NCT02458235 PHASE2 COMPLETED Results posted

The goal of this study is to determine whether post-transplant consolidation with azacitidine combined with donor lymphocyte infusion (DLI) is a safe and effective approach for the prevention of relapse in pediatric and young adult patients with hematologic malignancies who have undergone hematopoietic stem cell transplantation (HSCT).

Details

Lead sponsor	University of California, San Francisco
Phase	PHASE2
Status	COMPLETED
Enrolment	17
Start date	Tue Jun 02 2015 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Fri Mar 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Acute Myelogenous Leukemia
• Acute Lymphoid Leukemia
• Juvenile Myelomonocytic Leukemia
• Myelodysplastic Syndrome

Interventions

• azacitidine
• donor lymphocyte infusion

Countries

United States