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Retinoic Acid Homeostasis in Neuropsychiatric Diseases (RAHND)
It is hypothesized, that local retinoic acid (RA) homeostasis is functionally involved in the pathophysiology of depression. In a cross-sectional (and partly longitudinal) analysis, serum RA status will be assessed in healthy controls and subjects with Major Depression, Alzheimer's disease, alcoholism and in subjects with schizophrenia.
Details
| Lead sponsor | Charite University, Berlin, Germany |
|---|---|
| Status | UNKNOWN |
| Enrolment | 200 |
| Start date | 2015-03 |
| Completion | 2022-12 |
Conditions
- Major Depression
- Alzheimer's Disease
- Alcoholism
- Schizophrenia
Primary outcomes
- Serum retinoic acid (RA) levels [nM] — Week 0
Serum retinoic acid levels \[nM\] as determined by HPLC according to previously published protocols
Countries
Germany