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Comparison of Intratechal Low-Dose Levobupivacaine With Levobupivacaine-Fentanyl and Levobupivacaine-Sufentanil Combinations for Cesarean Section
45 pregnant women undergoing cesarean section were enrolled in the study in november 2006 to march 2007. 2 ml of 0.5% levobupivacaine was added to 1 ml of saline in group I, 1 ml of 15 µcg of fentanyl in group II and 1 ml of 1,5 µcg sufentanil in group III by intratechal administration. Hemodynamic parameters, characteristics of sensory and motor blockade, peri-operative and postoperative visual analogue scale (VAS) pain scores, the time to the first analgesic requirement and adverse effects were recorded.
Details
| Lead sponsor | Ankara City Hospital Bilkent |
|---|---|
| Phase | Phase 2 |
| Status | COMPLETED |
| Enrolment | 45 |
| Start date | 2006-11 |
| Completion | 2007-03 |
Conditions
- Anesthesia
Interventions
- Levobupivacaine
- Fentanyl
- Sufentanil
- Levobupivacaine
- Levobupivacaine
Primary outcomes
- Number of Participants With Adverse Events as a Measure of Safety and Tolerability — Up to 4 months
The frequency and the severity (ex) of the side effects including nausea and vomiting, hypotension, pruritus, and bradycardia were recorded.