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Investigation of the Clinical Use of Different Analgesia-Monitors for Tracing Unconscious Pain Sensations During General Anesthesia (AMUPS)
Until today there is no standard-monitoring to specifically reflect the analgesic component of general anesthesia. Quality and safety of general anesthesia are of major clinical importance and can be improved by limiting the administration of opioid analgesics to the minimum dose needed. This study therefore examines the quality of three different monitoring techniques (PhysioDoloris, MetroDoloris, Lille, France, SPI (Surgical Plethysmographic Index), GE Healthcare, Helsinki, Finland and AlgiScan, IDMed, Marseille, France) in assessing the level of analgesia during general anesthesia. Therefore a standardized painful stimulus is applied under different levels of analgesic drugs. The monitor's indices are compared to clinical signs such as an increase in heart rate and blood pressure.
Details
| Lead sponsor | Universitätsklinikum Hamburg-Eppendorf |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 30 |
| Start date | 2015-04 |
| Completion | 2015-09 |
Conditions
- Anesthesia
Interventions
- Analgesia monitor (PhysioDoloris®)
- Analgesia monitor (SPI®)
- Analgesia monitor (AlgiScan®)
- Remifentanil
Primary outcomes
- Comparison of the Pearson correlation coefficient between the dose of analgesic medication (remifentanil) on the one hand and the changes in heart rate, blood pressure and output of the analgesia monitoring systems on the other hand. — Observation for approximately 30 minutes after anesthesia induction
Countries
Germany