Acetazolamide and Hydrochlorothiazide Followed by Furosemide Versus Hydrochlorothiazide and Furosemide Followed by Furosemide for the Treatment of Adults With Refractory Nephrotic Edema: A Randomized, Double-Blind Trial

NCT02427880 Phase 4 COMPLETED

The purpose of this study is to determine whether using furosemide following acetazolamide is effective in treating refractory edema associated with nephrotic syndrome.

Details

Lead sponsor	Shiraz University of Medical Sciences
Phase	Phase 4
Status	COMPLETED
Enrolment	20
Start date	2015-04
Completion	2015-06

Conditions

• Nephrotic Syndrome
• Edema

Interventions

• Acetazolamide and Hydrochlorothiazide Followed by Furosemide
• Furosemide and Hydrochlorothiazide Followed by Furosemide

Primary outcomes

• Change from baseline in weight at the end of third week — Baseline and at the end of the third week