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Evaluation of Fractional CO2 Laser Treatment Efficacy and Comparison to Vaginal Estrogen Therapy in Postmenopausal Women With Vulvovaginal Atrophy
Forty-five women will be included in a double-blind randomized trial in order to compare fractional CO2 laser treatment, local estrogen therapy and the combination of both treatments for Vulvovaginal Atrophy (VVA) and determine the efficacy and possible adverse effects CO2 laser treatment.
Details
| Lead sponsor | Faculdade de Medicina do ABC |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 45 |
| Start date | 2015-03 |
| Completion | 2015-11 |
Conditions
- Vulvovaginal Atrophy
Interventions
- CO2 laser
- Estrogen
- Placebo of Estrogen
- Placebo of CO2 laser
Primary outcomes
- Change from Baseline in Vulvovaginal Symptom Questionnaire — Baseline, week 10 and week 17
Vulvovaginal Symptom Questionnaire will be used to evaluate improvement of vulvovaginal atrophy symptoms.
Countries
Brazil