In-vivo Non-invasive Skin Imaging Pilot Study to Assess the Effects of Tretinoin Cream Using Multi-photon Microscopy and Multi-spectral Imaging

NCT02410980 EARLY_PHASE1 COMPLETED

The researchers will assess the effects of treatment with tretinoin cream on human skin by using non-invasive optical imaging technologies.

Details

Lead sponsor	University of California, Irvine
Phase	EARLY_PHASE1
Status	COMPLETED
Enrolment	15
Start date	2015-08
Completion	2016-12

Conditions

• Collagen Fibril Alteration

Interventions

• Tretinoin cream 0.1%

Primary outcomes

• Skin Collagen/Elastin ratio over time - Change from baseline in sun exposed, and non sun exposed skin areas. — up to 2 months
  The effects of tretinoin cream on human skin will be measured.

Countries

United States