NCT02408289 is a NA clinical trial of Lo-Flav in Obesity, sponsored by Brooklyn College of the City University of New York.

Who is sponsoring NCT02408289?

NCT02408289 is sponsored by Brooklyn College of the City University of New York.

What drugs are being tested in NCT02408289?

Interventions in NCT02408289: Lo-Flav, Hi-Flav, Epicatechin, Procyanidins.

Is NCT02408289 still recruiting?

NCT02408289 is currently completed. Last updated 12 January 2016.

Last reviewed 2016-01-12 · How we verify

NCT02408289

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Pilot Randomized Human Trial on The Effects of Cocoa on Appetite.

Completed NA Last updated 12 January 2016

What this trial tests

NA trial testing Lo-Flav in Obesity in 28 participants. Completed in 1 May 2015.

Timeline

1 March 2015

Primary endpoint
1 May 2015

1 May 2015

Quick facts

Lead sponsor	Brooklyn College of the City University of New York
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	prevention
Enrollment	28
Start date	1 March 2015
Primary completion	1 May 2015
Estimated completion	1 May 2015
Sites	1 location across United States

Drugs / interventions tested

Lo-Flav
Hi-Flav
Epicatechin
Procyanidins

Conditions studied

Obesity — all drugs for Obesity →

Sponsor

Brooklyn College of the City University of New York

Who can join

Adults 18 to 35, male only, with Obesity. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Appetite as assessed by amount of pizza eaten.
Time frame: Two and a half hours
Amount of pizza eaten to be assessed two and one half hours after ingestion of the beverage.

Sponsor's own description

The purpose of this study is to determine whether high-flavonoid cocoa can decrease appetite in humans. In addition the study is designed to test epicatechin, a compound found in cocoa and procyanidins, a class of compounds found in cocoa, for their ability to decrease appetite in humans.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Proanthocyanidins and hydrolysable tannins: occurrence, dietary intake and pharmacological effects.
Smeriglio A, Barreca D, Bellocco E, Trombetta D. · · 2017 · cited 323× · PMID 27646690 · DOI 10.1111/bph.13630
Epicatechin, procyanidins, cocoa, and appetite: a randomized controlled trial.
Greenberg JA, O'Donnell R, Shurpin M, Kordunova D. · · 2016 · cited 11× · PMID 27510533 · DOI 10.3945/ajcn.115.129783

Verify or expand the search:

Other recruiting trials for Obesity

Currently open trials in the same condition.

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NCT07481630 — A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoart · Phase 3 · recruiting
NCT07527195 — Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscl · Phase 1 · recruiting

Other Brooklyn College of the City University of New York trials

Trials by the same sponsor.

NCT04749719 — At Home Brain Stimulation Studies of Memory and Memory Awareness · NA · unknown
NCT04026633 — Attitudes & College Experiences · NA · completed
NCT03693729 — Effects of Brain-stimulation on Metamemory Monitoring and Control · NA · unknown
NCT03453073 — Chocolate and CVD Risk in Postmenopausal Women · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02408289 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Brooklyn College of the City University of New York
Last refreshed: 12 January 2016

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02408289.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing