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NCT02405702

Importance of Patient Selection for Treatment of Infected Total Knee Prosthesis

Completed Last updated 5 September 2025
What this trial tests

trial testing restrospective study in Knee Infection in 60 participants. Completed in 31 January 2016.

Timeline
1 March 2015
Primary endpoint
31 January 2016
31 January 2016

Quick facts

Lead sponsorUniversity Hospital, Strasbourg, France
StatusCompleted
Study typeOBSERVATIONAL
Enrollment60
Start date1 March 2015
Primary completion31 January 2016
Estimated completion31 January 2016

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Strasbourg, France

Who can join

18 and older, any sex, with Knee Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The infection of a total knee replacement often imposes changing implants. The change in two step is currently considered the gold standard. The change in one step is a much debated attitude: strictly contra-indicated for some professionals, but others agree to reserve these for favorable suspected cases selected. Several criteria have been proposed in the literature: age, condition, duration of infection, known bacterium responsible, not virulent and sensitive to antibiotics, no fistula, no significant bone destruction. But these criteria are poorly validated, standing over an experience of surgical teams rather than high-level scientific studies. Some authors have proposed to achieve change in one step systematically. The results of these cohorts on healing the infection does not seem very different from the changes in two steps. But it is most often single-center series, uncontrolled, with small numbers.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Knee Infection

Currently open trials in the same condition.

Other University Hospital, Strasbourg, France trials

Trials by the same sponsor.

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Data sources for this page

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