NCT02399514 is a NA clinical trial of Polysomnographic diagnostic in COPD, sponsored by Institut für Pneumologie Hagen Ambrock eV.

Who is sponsoring NCT02399514?

NCT02399514 is sponsored by Institut für Pneumologie Hagen Ambrock eV.

What drugs are being tested in NCT02399514?

Interventions in NCT02399514: Polysomnographic diagnostic.

What condition does NCT02399514 study?

NCT02399514 studies COPD, Emphysema.

Is NCT02399514 still recruiting?

NCT02399514 is currently completed. Last updated 11 February 2019.

Last reviewed 2019-02-11 · How we verify

NCT02399514

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Improvement of Sleep Quality by RePneu® Coils in Advanced Pulmonary Emphysema

Completed NA Last updated 11 February 2019

What this trial tests

NA trial testing Polysomnographic diagnostic in COPD in 20 participants. Completed in 9 March 2018.

Timeline

5 November 2014

Primary endpoint
9 March 2018

9 March 2018

Quick facts

Lead sponsor	Institut für Pneumologie Hagen Ambrock eV
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	basic science
Enrollment	20
Start date	5 November 2014
Primary completion	9 March 2018
Estimated completion	9 March 2018
Sites	1 location across Germany

Drugs / interventions tested

Polysomnographic diagnostic

Conditions studied

COPD — all drugs for COPD →
Emphysema — all drugs for Emphysema →

Sponsor

Institut für Pneumologie Hagen Ambrock eV

Who can join

18 and older, any sex, with COPD or Emphysema. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Improvement of sleep quality in emphysema patients is desirable. Yet, there are no data of patients treated with RePneu coils. This monocenter prospective study investigates the effect on sleep quality of RePneu coils for reduction of dynamic hyperinflation in advanced disease stages of pulmonary emphysema. Patient's sleep will be studied in three Polysomnography measurement nights, one prior to Coil Treatment, one six months after, and one twelve month after. Primary objective is to investigate differences in sleep quality 6 and 12 months after Coil Treatment. Further endpoints are changes in daily activity and sleep (actigraphy), 6MWT, lung function parameters, and questionnaires (SGRQ, mMRC dyspnoe scale).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Lung volume reduction with endobronchial coils for patients with emphysema.
Welling JBA, Slebos DJ. · · 2018 · cited 14× · PMID 30210833 · DOI 10.21037/jtd.2017.12.95
Effects of endobronchial coils for endoscopic lung volume reduction on sleep in COPD patients with advanced pulmonary emphysema.
Franke KJ, Domanski U, Schröder M, Nilius G. · · 2021 · cited 1× · PMID 32845475 · DOI 10.1007/s11325-020-02176-0

Verify or expand the search:

Other recruiting trials for COPD

Currently open trials in the same condition.

NCT07344649 — Turkish Validation of the Nijmegen Questionnaire in COPD · recruiting
NCT07524023 — Emotional-distress-based Integrated Care Programme in Patients With Stable COPD · NA · recruiting
NCT07460154 — Structured Review: To Optimise Management and Prevent Harm in COPD · NA · recruiting
NCT07462221 — Effect of Telenursing on Oral Health · NA · recruiting
NCT07051707 — Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD · NA · recruiting

Other Institut für Pneumologie Hagen Ambrock eV trials

Trials by the same sponsor.

NCT05053074 — Nasal High Flow (NHF) in COPD - Effects on Ventilation in Wakefulness · NA · completed
NCT04407949 — Comparison of Sleep Disordered Breathing Events Detected by the CPAP Device "prismaLine" With Polysomnography · NA · completed
NCT04090671 — Evaluation of the Multidimensional Dyspnea Profile (MDP) · NA · unknown
NCT01986452 — Telemonitoring of CPAP Therapy in Apoplexy Patients With OSA · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT02399514 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Institut für Pneumologie Hagen Ambrock eV
Last refreshed: 11 February 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02399514.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing