Last reviewed · How we verify
NCT02379403
Effects of Tart Cherry and Aroniaberry Supplementation on Endothelial Function and Cardiovascular Measures in Healthy Older Adults: Interactions With Genotype and Proteome
trial in Cardiovascular Disease. Withdrawn.
9 May 2017
Quick facts
| Lead sponsor | National Institute of Nursing Research (NINR) |
|---|---|
| Status | Withdrawn |
| Study type | OBSERVATIONAL |
| Start date | 19 February 2015 |
| Primary completion | 9 May 2017 |
| Estimated completion | 9 May 2017 |
Conditions studied
- Cardiovascular Disease — all drugs for Cardiovascular Disease →
- Coronary Heart Disease — all drugs for Coronary Heart Disease →
- Aging — all drugs for Aging →
Sponsor
National Institute of Nursing Research (NINR)
Who can join
Adults 55 to 70, any sex, with Cardiovascular Disease or Coronary Heart Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: \- Heart disease is the leading cause of death and disabilities in the United States. Diets high in fruits and vegetables may reduce the risk of heart disease. Fruits, including red tart cherries and purple aroniaberries, may be especially beneficial. Researchers want to know how tart cherry and aroniaberry extracts affect heart health. Objective: \- To study the benefits of tart cherry and aroniaberry extract on vascular function and other measures. These include inflammation, oxidation, and cholesterol. Eligibility: \- Men and post-menopausal women ages 55 70 in good health and with normal or slightly high blood pressure or cholesterol. Design: * Participants will be screened with a physical exam, medical history, and blood tests. * Participants will have 6 visits. They will have blood taken at every visit. * Visit 1: * Blood vessel tests. Participants will lie down. Heart rhythm will be monitored. A device will be placed on the upper arm, and pictures of blood vessels will be taken. * A blood pressure cuff will be tightened around the lower arm for 5 minutes. * Cardio-Ankle-Vascular Index (CAVI). Blood pressure cuffs will be placed on both arms and legs. They will be tightened with air at the same time for a few minutes. * Participants will be assigned to one of three groups. For 3 weeks each, in random order, they will take: aroniaberry capsules, tart cherry capsules, placebo capsules, and no capsules. * Participants will answer questions online about their eating and exercise. * Participants will be keep a record of what they eat for a few periods. They will come for a study visit every 3 weeks through week 15.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT02379403
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT02379403 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Nursing Research (NINR)
- Last refreshed: 6 October 2017
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT02379403.
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