Last reviewed · How we verify
Mechanisms of Refractory Hypertension (Carvedilol)
The purpose of this protocol is test whether patients with hypertension refractory to antihypertensive treatment have evidence of excessive sympathetic (i.e., nervous system) activity.
Details
| Lead sponsor | University of Alabama at Birmingham |
|---|---|
| Phase | NA |
| Status | WITHDRAWN |
| Start date | 2015-02 |
| Completion | 2020-01-31 |
Conditions
- Hypertensive
Interventions
- Carvedilol
- Chlorthalidone
Primary outcomes
- % of subjects who achieve BP control (<140/90 mm Hg) — 8 weeks after baseline
BP will be measured 8 weeks after starting carvedilol and after starting chlorthaidone. The percent of subjects with BP of \<140/90 mm HG in each group will be reported.