Comparative Effects of Moxonidine and Bisoprolol on Bone Metabolism, Vascular and Cellular Markers of Aging, Blood Pressure in Hypertensive Postmenopausal Women (COMPASS)

NCT02355821 NA COMPLETED Results posted

This study evaluates the effect of moxonidine versus bisoprolol on collagen type 1 C-telopeptide in postmenopausal female patients with arterial hypertension and osteopenia.

Details

Lead sponsor	National Research Center for Preventive Medicine
Phase	NA
Status	COMPLETED
Enrolment	114
Start date	2015-04
Completion	2018-07-10

Conditions

• Osteopenia
• Arterial Hypertension

Interventions

• Moxonidine
• Bisoprolol

Primary outcomes

• Collagen Type 1 C-telopeptide — baseline (Visit 1) and 12 months (Visit 4)
  Changes in Median (Inter-Quartile Range) of the bone resorption marker (collagen type 1 C-telopeptide) at the end of the study from the baseline are evaluated in comparison between the groups

Countries

Russia