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Efficacy of Parietal Continuous Infiltration of Local Anesthesic on Diaphragmatic Function After Upper Abdominal Surgery Through a Subcostal Incision (CATPAR)
Upper abdominal surgery is known to induce such pulmonary complications as pneumonia, atelectasis, pleural effusion. The post operative diaphragmatic dysfunction participates to these complications and lasts for 7 days after upper abdominal surgery. The sniff-test is a recognized tool for measuring the diaphragmatic function.The purpose of this study is to evaluate the effectiveness of parietal analgesia with continuous infiltration of local anesthesic on diaphragmatic function after upper abdominal surgery through a subcostal incision. Our main outcome is to measure the diaphragmatic function with the sniff test in 44 patients with parietal infiltration of ropivacaine and in 44 patients with placebo. Our secondary outcomes are the evaluation of the effect of continuous parietal analgesia with ropivacaine on IPmax and EPmax, oxygen saturation, post operative pulmonary complications and post operative recovery. This prospective study will determine if the pre peritoneal local infiltration of ropivacaine is useful to decrease post operative diaphragmatic dysfunction.
Details
| Lead sponsor | University Hospital, Rouen |
|---|---|
| Phase | Phase 3 |
| Status | TERMINATED |
| Enrolment | 31 |
| Start date | 2014-07 |
| Completion | 2017-06 |
Conditions
- Hepatectomy
Interventions
- Sniff test
- Infusion of Ropivacaine during 48 hours
- Continuous parietal infusion with parietal catheter
- Infusion of placebo during 48 hours
- NaCl
Primary outcomes
- Buccal Inspiratory Pression (IP) Evaluation of diaphragmatic function using sniff test. — Day 6 post surgery
Evaluation of diaphragmatic function using sniff test. The measured value is buccal inspiratory pression.
Countries
France